Successful Prophylactic Endovascular Therapy for a Rapidly Expanding Hepatic Arterial Aneurysm in a Patient with Vascular Ehlers–Danlos Syndrome

• Published in: Annals of Vascular Diseases Vol. 14; no. 2; pp. 163 - 167
• Main Authors: Watanabe, Yukihiro, Akutsu, Koichi, Yasui, Daisuke, Sugihara, Fumie, Miyachi, Hideki, Hayashi, Hiroshi, Oka, Eiichiro, Komiyama, Hidenori, Kumita, Shin-ichiro, Shimizu, Wataru
• Format: Journal Article
• Language: English
• Published: Italian Cultural Institute Building 8F, Kudan-Minami 2-1-30, Chiyoda-ku, Tokyo 102-0074, Japan The Editorial Committee of Annals of Vascular Diseases 25.06.2021; Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology
• Subjects: Case Report; Ehlers–Danlos syndrome type IV; prophylactic endovascular therapy; rapid expansion of arterial aneurysm
• ISSN: 1881-641X; 1881-6428
• DOI: 10.3400/avd.cr.20-00144

Vascular Ehlers–Danlos syndrome (vEDS) causes fatal vascular complications due to vascular fragility. However, invasive therapeutic procedures are generally avoided except in emergencies. We report a case of vEDS presenting with rapid expansion of a hepatic arterial aneurysm successfully treated using prophylactic endovascular therapy. A 43-year-old woman with vEDS confirmed by genetic testing was hospitalized for a symptomatic hepatic arterial aneurysm that expanded rapidly within a week. Prophylactic coil embolization was then successfully performed. Although the general applicability of this approach cannot be determined, prophylactic endovascular therapy can clearly be an option for arterial aneurysms at high risk of rupture.