An Overview on the Primary Factors That Contribute to Non-Allergic Asthma in Children

The prevalence of non-allergic asthma in childhood is low, peaking in late adulthood. It is triggered by factors other than allergens, like cold and dry air, respiratory infections, hormonal changes, smoke and air pollution. In the literature, there are few studies that describe non-allergic asthma...

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Published inJournal of clinical medicine Vol. 11; no. 21; p. 6567
Main Authors Klain, Angela, Dinardo, Giulio, Salvatori, Alessandra, Indolfi, Cristiana, Contieri, Marcella, Brindisi, Giulia, Decimo, Fabio, Zicari, Anna Maria, Miraglia del Giudice, Michele
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 05.11.2022
MDPI
Subjects
Allergens
Allergies
Antigens
Asthma
Chemokines
children
Cytokines
Exercise
exercise-induced asthma
Histamine
Infections
Inflammation
Ligands
Neutrophils
non-allergic asthma
Peptides
Physical fitness
pollution
premenstrual asthma
Respiratory syncytial virus
Review
Smooth muscle
Steroids
Viral infections
Viruses
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Summary:The prevalence of non-allergic asthma in childhood is low, peaking in late adulthood. It is triggered by factors other than allergens, like cold and dry air, respiratory infections, hormonal changes, smoke and air pollution. In the literature, there are few studies that describe non-allergic asthma in pediatric age. Even though it is a less common disorder in kids, it is crucial to identify the causes in order to keep asthma under control, particularly in patients not responding to conventional treatments. In this review, we discuss non-IgE-mediated forms of asthma, collecting the latest research on etiopathogenesis and treatment.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11216567