Surgical intervention in aggressive ulcerative pyoderma gangrenosum

Pyoderma Gangrenosum (PG) is a rare, debilitating, and painful disease of the skin. Its aetiology and pathophysiology are not well understood. However, it is known that PG is not bacterial in origin, as previously believed. A significant number of cases of PG report a phenomenon called pathergy, whi...

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Published inJournal of the Pakistan Medical Association Vol. 72; no. 1; pp. 152 - 154
Main Authors Mudassir, Maham, Ali, Rabia, Saeed, Sikandar, Mirza, Ali Rafique
Format Journal Article
LanguageEnglish
Published Pakistan Knowledge Bylanes 01.01.2022
Pakistan Medical Association
Subjects
Adult
Care and treatment
Case studies
Female
Gangrene
Humans
Pyoderma
Pyoderma Gangrenosum
Skin
Skin Transplantation
Skin-grafting
Ulcers
Young Adult
Pakistan
pyoderma gangrenosum, wound, split thickness skin grafting
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Summary:Pyoderma Gangrenosum (PG) is a rare, debilitating, and painful disease of the skin. Its aetiology and pathophysiology are not well understood. However, it is known that PG is not bacterial in origin, as previously believed. A significant number of cases of PG report a phenomenon called pathergy, which is characterized by the appearance of new lesions after the application of trauma to the skin. This represents a unique challenge for surgeons in cases that are refractory to medical therapy. The objective of this study is to review past literature and report a case of PG in a 19-year old woman, who presented with recurrence, after undergoing skin grafting one year back. The patient was referred for split thickness skin grafting (STSG) to reduce the psychological and physical morbidity as a result of this disease.
Bibliography:ObjectType-Case Study-2
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ObjectType-Review-3
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ISSN:0030-9982
DOI:10.47391/JPMA.11-1109