Effect of the consumption on buriti oil on the metabolism of rats induced by iron overload

• Published in: Archives of Endocrinology and Metabolism Vol. 59; no. 5; pp. 422 - 427
• Main Authors: Aquino, Jailane de Souza, Tavares, Renata Leite, Medeiros, Larissa de Brito, Martins, Camila Cândida de Lima, Pessoa, Débora Catarine Nepomuceno de Pontes, Stamford, Tânia Lúcia Montenegro
• Format: Journal Article
• Language: English
• Published: Brazil Brazilian Society of Endocrinology and Metabolism 01.10.2015
• Subjects: Animals; Body Weight - drug effects; Carotenoids - pharmacology; Dietary Fats - administration & dosage; Dietary Fats - analysis; Fatty Acids - analysis; Fatty Acids, Unsaturated - analysis; Iron overload; Iron Overload - chemically induced; Iron Overload - metabolism; Liver - metabolism; Male; Models, Animal; oxidative stress; Oxidative Stress - drug effects; Plant Oils - pharmacology; Random Allocation; Rats, Wistar; Soybean Oil - pharmacology; Triglycerides - blood; vegetable oils; Weight Gain; Wistar rats
• ISSN: 2359-3997; 2359-4292; 2359-4292; 2359-3997
• DOI: 10.1590/2359-3997000000105

To compare the effect of the consumption of buriti oil and soybean oil on the metabolism of rats under stress induced by iron overload. A total of 28 rats were randomized into control groups who consumed diet added of soybean (CS) or buriti oil (CB) and gavage with saline and two experimental groups who consumed diet added of soybean (ES) or buriti oil (EB) and daily gavage with iron II sulfate as stress inducer. The fatty acid profile of diets was analyzed. Body weight and diet consumption were evaluated every two days. The lipid profile and liver weight of animals were evaluated at the end of the experiment. Diet added of soybean oil showed higher percentage of polyunsaturated fatty acids (45.6%) and diet with buriti oil was rich in monounsaturated fatty acids (66.9%). There were no differences in food intake, total cholesterol, HDL-cholesterol and LDL-cholesterol among groups (p > 0.05). However, animals fed with diet supplemented with buriti oil showed intermediate triglyceride levels (CB: 65 mg/dL; EB: 68.7 mg/dL) compared to ES group (102.5 mg/dL). The liver of rats from the CS group had higher weight (2.06 ± 0.2 g) compared to the CB group (1.56 ± 0.1 g). Buriti oil consumption was able to minimize some changes related to iron overload.