Optofluidic imaging: now and beyond

More than a decade of research work in optofluidics has yielded a large catalogue of optofluidic elements that can manipulate light at the micro-scale (e.g., lenses, prisms). Although these elements have proven useful for many on-chip processes (e.g., miniaturized flow cytometry, interferometry and...

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Published inLab on a chip Vol. 13; no. 1; pp. 17 - 24
Main Authors Zhao, Yanhui, Stratton, Zackary S, Guo, Feng, Lapsley, Michael Ian, Chan, Chung Yu, Lin, Sz-Chin Steven, Huang, Tony Jun
Format Journal Article
LanguageEnglish
Published England 07.01.2013
Subjects
Animals
Catalogues
Flow cytometry
Fluorescent Dyes - chemistry
Imaging
Microfluidic Analytical Techniques - instrumentation
Microfluidic Analytical Techniques - methods
Microfluidic Analytical Techniques - trends
Microscopy - methods
Nematoda
Optical Imaging - instrumentation
Optical Imaging - methods
Optical Imaging - trends
Prisms
Three dimensional
Tomography
Tomography - methods
Two dimensional
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Summary:More than a decade of research work in optofluidics has yielded a large catalogue of optofluidic elements that can manipulate light at the micro-scale (e.g., lenses, prisms). Although these elements have proven useful for many on-chip processes (e.g., miniaturized flow cytometry, interferometry and sample spectroscopy), certain deficiencies have precluded their use in micro-scale imaging. However, recent work in optofluidic imaging has avoided optofluidic elements entirely and focused instead on image capture and composition techniques, demonstrating impressive resolution in both 2D imagery and 3D tomography. In this Focus article, we will discuss some of the recent successes in optofluidic imaging and will expound our expectations for the near future of the optofluidic imaging discipline.
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ISSN:1473-0197
1473-0189
DOI:10.1039/c2lc90127g