In vitro antibacterial screening of Cryptolepis sanguinolenta alkaloids

The ethanol and aqueous crude extracts and five alkaloids isolated from the roots of Crytolepis sanguinolenta (Lindl.) Schlechter were screened for antibacterial activity against 7 reference strains by the twofold serial broth microdilution assay. The ethanol extract and the alkaloids cryptolepine a...

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Bibliographic Details
Published inJournal of ethnopharmacology Vol. 44; no. 2; pp. 127 - 130
Main Authors Paulo, Alexandra, Duarte, Aida, Gomes, Elsa T.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.10.1994
Elsevier
Subjects
Alkaloids - pharmacology
Antibacterial activity
Bacteria - drug effects
Biological and medical sciences
Cryptoheptine
Cryptolepine
Cryptolepis sanguinolenta
General pharmacology
In Vitro Techniques
Indol alkaloids
Medical sciences
Medicine, African Traditional
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plants, Medicinal
West Africa
Africa
Indol alkaloids
Cryptoheptine
Antibacterial activity
Cryptolepine
Cryptolepis sanguinolenta
Root
Pharmacognosy
Asclepiadaceae
In vitro
Biological activity
Medicinal plant
Alkaloid
Folk medicine
Dicotyledones
Angiospermae
Plant origin
Isolation
Spermatophyta
Antibacterial agent
Indole derivatives
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Summary:The ethanol and aqueous crude extracts and five alkaloids isolated from the roots of Crytolepis sanguinolenta (Lindl.) Schlechter were screened for antibacterial activity against 7 reference strains by the twofold serial broth microdilution assay. The ethanol extract and the alkaloids cryptolepine and cryptoheptine inhibited the growth of all strains tested except that of Pseudomonas aeruginosa.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0378-8741
1872-7573
DOI:10.1016/0378-8741(94)90079-5