Evaluation of chitoligosaccharides effect upon probiotic bacteria

The main objective of the present study was to evaluate the antibacterial effect – through the determination of minimum inhibitory (and lethal) concentrations, as well as the possible prebiotic potential of chitooligosaccharides (COS) – through the determination of growth curves, on Bifidobacterium...

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Published inInternational journal of biological macromolecules Vol. 50; no. 1; pp. 148 - 152
Main Authors Fernandes, João C., Eaton, Peter, Franco, Isabel, Ramos, Óscar S., Sousa, Sérgio, Nascimento, Henrique, Gomes, Ana, Santos-Silva, Alice, Xavier Malcata, F., Pintado, Manuela E.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.2012
Subjects
Anti-Bacterial Agents - chemistry
antibacterial properties
Atomic force microscopy
bacteria
Bifidobacterium - metabolism
Bifidobacterium animalis
carbon
Carbon - chemistry
cell biology
Chitin - chemistry
Chitooligosaccharides
Chitosan
Culture Media - chemistry
Glucose - chemistry
Hydrogen-Ion Concentration
Lactobacillus acidophilus
Lactobacillus acidophilus - metabolism
Microbial Sensitivity Tests
Microscopy, Atomic Force - methods
nutrient uptake
Oligosaccharides - chemistry
prebiotics
Probiotic bacteria
probiotics
Probiotics - metabolism
Time Factors
Probiotic bacteria
Atomic force microscopy
Chitosan
Chitooligosaccharides
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Abstract The main objective of the present study was to evaluate the antibacterial effect – through the determination of minimum inhibitory (and lethal) concentrations, as well as the possible prebiotic potential of chitooligosaccharides (COS) – through the determination of growth curves, on Bifidobacterium animalis Bb12, Bifidobacterium animalis Bo and Lactobacillus acidophilus Ki. Atomic force microscopy was further used to obtain high resolution images of COS effects upon the cell morphology. Our results demonstrate that COS do not stimulate the growth of those strains, neither the strains are capable of using COS as a primary source of carbon. Analysis of morphology when exposed to inhibitory/bactericidal concentrations, suggested that COS do not exert any direct damage upon the bacteria structure, instead the bacteria are apparently covered by COS, which likely prevent nutrient uptake.
AbstractList The main objective of the present study was to evaluate the antibacterial effect - through the determination of minimum inhibitory (and lethal) concentrations, as well as the possible prebiotic potential of chitooligosaccharides (COS) - through the determination of growth curves, on Bifidobacterium animalis Bb12, Bifidobacterium animalis Bo and Lactobacillus acidophilus Ki. Atomic force microscopy was further used to obtain high resolution images of COS effects upon the cell morphology. Our results demonstrate that COS do not stimulate the growth of those strains, neither the strains are capable of using COS as a primary source of carbon. Analysis of morphology when exposed to inhibitory/bactericidal concentrations, suggested that COS do not exert any direct damage upon the bacteria structure, instead the bacteria are apparently covered by COS, which likely prevent nutrient uptake.The main objective of the present study was to evaluate the antibacterial effect - through the determination of minimum inhibitory (and lethal) concentrations, as well as the possible prebiotic potential of chitooligosaccharides (COS) - through the determination of growth curves, on Bifidobacterium animalis Bb12, Bifidobacterium animalis Bo and Lactobacillus acidophilus Ki. Atomic force microscopy was further used to obtain high resolution images of COS effects upon the cell morphology. Our results demonstrate that COS do not stimulate the growth of those strains, neither the strains are capable of using COS as a primary source of carbon. Analysis of morphology when exposed to inhibitory/bactericidal concentrations, suggested that COS do not exert any direct damage upon the bacteria structure, instead the bacteria are apparently covered by COS, which likely prevent nutrient uptake.
The main objective of the present study was to evaluate the antibacterial effect - through the determination of minimum inhibitory (and lethal) concentrations, as well as the possible prebiotic potential of chitooligosaccharides (COS) - through the determination of growth curves, on Bifidobacterium animalis Bb12, Bifidobacterium animalis Bo and Lactobacillus acidophilus Ki. Atomic force microscopy was further used to obtain high resolution images of COS effects upon the cell morphology. Our results demonstrate that COS do not stimulate the growth of those strains, neither the strains are capable of using COS as a primary source of carbon. Analysis of morphology when exposed to inhibitory/bactericidal concentrations, suggested that COS do not exert any direct damage upon the bacteria structure, instead the bacteria are apparently covered by COS, which likely prevent nutrient uptake.
Author Eaton, Peter
Fernandes, João C.
Sousa, Sérgio
Gomes, Ana
Ramos, Óscar S.
Santos-Silva, Alice
Nascimento, Henrique
Pintado, Manuela E.
Xavier Malcata, F.
Franco, Isabel
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  surname: Xavier Malcata
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Cites_doi 10.1016/S0168-1605(01)00717-6
10.1021/bm800622f
10.1016/S0304-3991(03)00045-7
10.1016/S0963-9969(01)00171-5
10.1021/bp049742c
10.1002/sia.2506
10.1016/j.foodchem.2010.04.061
10.1016/j.biomaterials.2006.11.006
10.1079/BJN/2002537
10.1128/JB.186.11.3286-3295.2004
10.1631/jzus.B0820261
10.1128/AAC.44.12.3456-3460.2000
10.1093/jn/125.6.1401
10.1016/S0008-6215(00)90359-8
10.1016/j.foodres.2010.09.010
10.3168/jds.S0022-0302(98)75840-0
10.1016/j.idairyj.2007.08.013
10.1016/S0304-3991(00)00075-9
10.1248/cpb.37.3026
10.1016/j.jconrel.2004.10.012
10.1016/j.ultramic.2009.03.015
10.1023/B:ABIM.0000025947.84650.b4
10.1016/j.ultramic.2008.04.015
10.1016/S1075-9964(03)00030-1
10.1016/j.carbpol.2005.10.028
10.1111/j.1349-7006.1990.tb02559.x
10.1128/AEM.02470-06
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Issue 1
Keywords Probiotic bacteria
Atomic force microscopy
Chitosan
Chitooligosaccharides
Language English
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References Uchida, Izume, Ohtakara (bib0130) 1989
Boyle-Vavra, Hahm, Sibener, Daum (bib0110) 2000; 44
Ruas-Madiedo, Moreno, Salazar, Delgado, Mayo, Margolles, Reyes-Gavilán (bib0150) 2007; 73
Fernandes, Eaton, Nascimento, Belo, Rocha, Vitorino, Amado, Gomes, Santos-Silva, Pintado, Malcata (bib0070) 2008; 9
Gibson, Roberfroid (bib0010) 1995; 125
Hyean-Woo, Yoon-Sun, Jong-Soo, Woo-Seob (bib0025) 2002; 8
Holzapfel, Schillinger (bib0005) 2002; 35
Sanders (bib0055) 2003; 61
Giustina, Ventura (bib0035) 1995; 16
Gomes, Malcata, Klaver (bib0125) 1998; 81
Fernandes, Eaton, Gomes, Pintado, Malcata (bib0155) 2009; 109
Chae, Jang, Nah (bib0065) 2005; 102
Gerasimenko, Avdienko, Bannikova, Zueva, Varlamov (bib0135) 2003; 40
Madureira, Amorim, Gomes, Pintado, Malcata (bib0120) 2011; 44
Eaton, West (bib0075) 2010
Eaton, Fernandes, Pereira, Pintado, Malcata (bib0165) 2008; 108
Suzuki, Mikami, Okawa, Tokoro, Suzuki, Suzuki (bib0040) 1986; 151
Pan, Chen, Wu, Tang, Zhao (bib0160) 2009; 10
Doktycz, Sullivan, Hoyt, Pelletier, Wu, Allison (bib0095) 2003; 97
Huebner, Wehling, Parkhurst, Hutkins (bib0020) 2008; 18
No, Park, Lee, Meyers (bib0140) 2002; 74
Liu, Chen, Park, Liu, Liu, Meng, Yu (bib0050) 2006; 64
Kolida, Tuohy, Gibson (bib0015) 2002; 87
Bolshakova, Kiselyova, Filonov, Frolova, Lyubchenko, Yaminsky (bib0090) 2001; 86
Macchi (bib0030) 1996; 27
Alhaj, Kanekanian, Peters, Tatham (bib0115) 2010; 123
Tsukada, Matsumoto, Aizawa, Tokoro, Naruse, Suzuki, Suzuki (bib0045) 1990; 81
Zhao, Schaefer, Marten (bib0100) 2005; 71
Gonzalez, Apella, Romero, Pesce de Ruiz Holgado, Oliver (bib0145) 1989; 37
Lin, Chen, Lee, Lee, Lin, Chiu (bib0060) 2007; 28
Wright, Armstrong (bib0080) 2006; 38
Touhami, Jericho, Beveridge (bib0105) 2004; 186
Bolshakova, Kiselyova, Yaminsky (bib0085) 2004; 20
Hyean-Woo (10.1016/j.ijbiomac.2011.10.011_bib0025) 2002; 8
Bolshakova (10.1016/j.ijbiomac.2011.10.011_bib0085) 2004; 20
Touhami (10.1016/j.ijbiomac.2011.10.011_bib0105) 2004; 186
Boyle-Vavra (10.1016/j.ijbiomac.2011.10.011_bib0110) 2000; 44
Fernandes (10.1016/j.ijbiomac.2011.10.011_bib0070) 2008; 9
Zhao (10.1016/j.ijbiomac.2011.10.011_bib0100) 2005; 71
Lin (10.1016/j.ijbiomac.2011.10.011_bib0060) 2007; 28
Giustina (10.1016/j.ijbiomac.2011.10.011_bib0035) 1995; 16
Bolshakova (10.1016/j.ijbiomac.2011.10.011_bib0090) 2001; 86
Gibson (10.1016/j.ijbiomac.2011.10.011_bib0010) 1995; 125
Fernandes (10.1016/j.ijbiomac.2011.10.011_bib0155) 2009; 109
Holzapfel (10.1016/j.ijbiomac.2011.10.011_bib0005) 2002; 35
Wright (10.1016/j.ijbiomac.2011.10.011_bib0080) 2006; 38
Alhaj (10.1016/j.ijbiomac.2011.10.011_bib0115) 2010; 123
Doktycz (10.1016/j.ijbiomac.2011.10.011_bib0095) 2003; 97
Uchida (10.1016/j.ijbiomac.2011.10.011_bib0130) 1989
Tsukada (10.1016/j.ijbiomac.2011.10.011_bib0045) 1990; 81
Macchi (10.1016/j.ijbiomac.2011.10.011_bib0030) 1996; 27
Sanders (10.1016/j.ijbiomac.2011.10.011_bib0055) 2003; 61
Kolida (10.1016/j.ijbiomac.2011.10.011_bib0015) 2002; 87
Madureira (10.1016/j.ijbiomac.2011.10.011_bib0120) 2011; 44
Ruas-Madiedo (10.1016/j.ijbiomac.2011.10.011_bib0150) 2007; 73
Eaton (10.1016/j.ijbiomac.2011.10.011_bib0165) 2008; 108
Pan (10.1016/j.ijbiomac.2011.10.011_bib0160) 2009; 10
Chae (10.1016/j.ijbiomac.2011.10.011_bib0065) 2005; 102
Suzuki (10.1016/j.ijbiomac.2011.10.011_bib0040) 1986; 151
Huebner (10.1016/j.ijbiomac.2011.10.011_bib0020) 2008; 18
No (10.1016/j.ijbiomac.2011.10.011_bib0140) 2002; 74
Gomes (10.1016/j.ijbiomac.2011.10.011_bib0125) 1998; 81
Gerasimenko (10.1016/j.ijbiomac.2011.10.011_bib0135) 2003; 40
Gonzalez (10.1016/j.ijbiomac.2011.10.011_bib0145) 1989; 37
Liu (10.1016/j.ijbiomac.2011.10.011_bib0050) 2006; 64
Eaton (10.1016/j.ijbiomac.2011.10.011_bib0075) 2010
References_xml – volume: 108
  start-page: 1128
  year: 2008
  end-page: 1134
  ident: bib0165
  publication-title: Ultramicroscopy
– volume: 8
  start-page: 319
  year: 2002
  end-page: 324
  ident: bib0025
  publication-title: Anaerobe
– volume: 86
  start-page: 121
  year: 2001
  end-page: 128
  ident: bib0090
  publication-title: Ultramicroscopy
– volume: 28
  start-page: 1355
  year: 2007
  end-page: 1366
  ident: bib0060
  publication-title: Biomaterials
– volume: 9
  start-page: 3346
  year: 2008
  end-page: 3352
  ident: bib0070
  publication-title: Biomacromolecules
– volume: 71
  start-page: 955
  year: 2005
  end-page: 960
  ident: bib0100
  publication-title: Appl. Biochem. Microbiol.
– volume: 10
  start-page: 258
  year: 2009
  end-page: 263
  ident: bib0160
  publication-title: J. Zhejiang Univ. Sci. B
– volume: 186
  start-page: 3286
  year: 2004
  end-page: 3295
  ident: bib0105
  publication-title: J. Bacteriol.
– volume: 87
  start-page: S193
  year: 2002
  end-page: S197
  ident: bib0015
  publication-title: Br. J. Nutr.
– volume: 16
  start-page: 199
  year: 1995
  end-page: 214
  ident: bib0035
  publication-title: Acta Toxicol. Therap.
– volume: 81
  start-page: 2817
  year: 1998
  end-page: 2825
  ident: bib0125
  publication-title: J. Dairy Sci.
– volume: 27
  start-page: 303
  year: 1996
  end-page: 320
  ident: bib0030
  publication-title: Acta Toxicol. Therap.
– volume: 40
  start-page: 253
  year: 2003
  end-page: 257
  ident: bib0135
  publication-title: Appl. Biochem. Microbiol.
– volume: 73
  start-page: 4385
  year: 2007
  end-page: 4388
  ident: bib0150
  publication-title: Appl. Environm. Microbiol.
– volume: 35
  start-page: 109
  year: 2002
  end-page: 116
  ident: bib0005
  publication-title: Food Res. Int.
– volume: 125
  start-page: 1401
  year: 1995
  end-page: 1412
  ident: bib0010
  publication-title: J. Nutr.
– volume: 64
  start-page: 60
  year: 2006
  end-page: 65
  ident: bib0050
  publication-title: Carbohydr. Polym.
– volume: 109
  start-page: 854
  year: 2009
  end-page: 860
  ident: bib0155
  publication-title: Ultramicroscopy
– volume: 102
  start-page: 383
  year: 2005
  end-page: 394
  ident: bib0065
  publication-title: J. Control Release
– volume: 44
  start-page: 3456
  year: 2000
  end-page: 3460
  ident: bib0110
  publication-title: Antimicrob. Agent. Chemoth.
– volume: 97
  start-page: 209
  year: 2003
  end-page: 216
  ident: bib0095
  publication-title: Ultramicroscopy
– volume: 38
  start-page: 1419
  year: 2006
  end-page: 1428
  ident: bib0080
  publication-title: Surf. Interf. Anal.
– volume: 44
  start-page: 465
  year: 2011
  end-page: 470
  ident: bib0120
  publication-title: Food Res. Int.
– start-page: 373
  year: 1989
  end-page: 382
  ident: bib0130
  publication-title: Chitin and Chitosan: Sources, Chemistry Biochemistry, Physical Properties and Applications
– year: 2010
  ident: bib0075
  article-title: Atomic Force Microscopy
– volume: 20
  start-page: 1615
  year: 2004
  end-page: 1622
  ident: bib0085
  publication-title: Biotechnol. Progr.
– volume: 18
  start-page: 287
  year: 2008
  end-page: 293
  ident: bib0020
  publication-title: Int. Dairy J.
– volume: 61
  start-page: 91
  year: 2003
  end-page: 99
  ident: bib0055
  publication-title: Nutr. Res.
– volume: 151
  start-page: 403
  year: 1986
  end-page: 408
  ident: bib0040
  publication-title: Carbohydr. Res.
– volume: 74
  start-page: 65
  year: 2002
  end-page: 72
  ident: bib0140
  publication-title: Int. J. Food Microbiol.
– volume: 81
  start-page: 259
  year: 1990
  end-page: 265
  ident: bib0045
  publication-title: Jpn. J. Canc. Res.
– volume: 123
  start-page: 430
  year: 2010
  end-page: 435
  ident: bib0115
  publication-title: Food Chem.
– volume: 37
  start-page: 3026
  year: 1989
  end-page: 3028
  ident: bib0145
  publication-title: Chem. Pharm. Bull. (Tokyo)
– volume: 74
  start-page: 65
  year: 2002
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0140
  publication-title: Int. J. Food Microbiol.
  doi: 10.1016/S0168-1605(01)00717-6
– volume: 9
  start-page: 3346
  year: 2008
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0070
  publication-title: Biomacromolecules
  doi: 10.1021/bm800622f
– start-page: 373
  year: 1989
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0130
– volume: 97
  start-page: 209
  year: 2003
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0095
  publication-title: Ultramicroscopy
  doi: 10.1016/S0304-3991(03)00045-7
– volume: 35
  start-page: 109
  year: 2002
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0005
  publication-title: Food Res. Int.
  doi: 10.1016/S0963-9969(01)00171-5
– volume: 20
  start-page: 1615
  year: 2004
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0085
  publication-title: Biotechnol. Progr.
  doi: 10.1021/bp049742c
– volume: 38
  start-page: 1419
  year: 2006
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0080
  publication-title: Surf. Interf. Anal.
  doi: 10.1002/sia.2506
– volume: 16
  start-page: 199
  year: 1995
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0035
  publication-title: Acta Toxicol. Therap.
– volume: 123
  start-page: 430
  year: 2010
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0115
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2010.04.061
– volume: 28
  start-page: 1355
  year: 2007
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0060
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2006.11.006
– volume: 87
  start-page: S193
  year: 2002
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0015
  publication-title: Br. J. Nutr.
  doi: 10.1079/BJN/2002537
– volume: 186
  start-page: 3286
  year: 2004
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0105
  publication-title: J. Bacteriol.
  doi: 10.1128/JB.186.11.3286-3295.2004
– volume: 10
  start-page: 258
  year: 2009
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0160
  publication-title: J. Zhejiang Univ. Sci. B
  doi: 10.1631/jzus.B0820261
– volume: 44
  start-page: 3456
  year: 2000
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0110
  publication-title: Antimicrob. Agent. Chemoth.
  doi: 10.1128/AAC.44.12.3456-3460.2000
– volume: 125
  start-page: 1401
  year: 1995
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0010
  publication-title: J. Nutr.
  doi: 10.1093/jn/125.6.1401
– volume: 151
  start-page: 403
  year: 1986
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0040
  publication-title: Carbohydr. Res.
  doi: 10.1016/S0008-6215(00)90359-8
– volume: 44
  start-page: 465
  year: 2011
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0120
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2010.09.010
– year: 2010
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0075
– volume: 71
  start-page: 955
  year: 2005
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0100
  publication-title: Appl. Biochem. Microbiol.
– volume: 81
  start-page: 2817
  year: 1998
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0125
  publication-title: J. Dairy Sci.
  doi: 10.3168/jds.S0022-0302(98)75840-0
– volume: 18
  start-page: 287
  year: 2008
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0020
  publication-title: Int. Dairy J.
  doi: 10.1016/j.idairyj.2007.08.013
– volume: 61
  start-page: 91
  year: 2003
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0055
  publication-title: Nutr. Res.
– volume: 27
  start-page: 303
  year: 1996
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0030
  publication-title: Acta Toxicol. Therap.
– volume: 86
  start-page: 121
  year: 2001
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0090
  publication-title: Ultramicroscopy
  doi: 10.1016/S0304-3991(00)00075-9
– volume: 37
  start-page: 3026
  year: 1989
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0145
  publication-title: Chem. Pharm. Bull. (Tokyo)
  doi: 10.1248/cpb.37.3026
– volume: 102
  start-page: 383
  year: 2005
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0065
  publication-title: J. Control Release
  doi: 10.1016/j.jconrel.2004.10.012
– volume: 109
  start-page: 854
  year: 2009
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0155
  publication-title: Ultramicroscopy
  doi: 10.1016/j.ultramic.2009.03.015
– volume: 40
  start-page: 253
  year: 2003
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0135
  publication-title: Appl. Biochem. Microbiol.
  doi: 10.1023/B:ABIM.0000025947.84650.b4
– volume: 108
  start-page: 1128
  year: 2008
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0165
  publication-title: Ultramicroscopy
  doi: 10.1016/j.ultramic.2008.04.015
– volume: 8
  start-page: 319
  year: 2002
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0025
  publication-title: Anaerobe
  doi: 10.1016/S1075-9964(03)00030-1
– volume: 64
  start-page: 60
  year: 2006
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0050
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2005.10.028
– volume: 81
  start-page: 259
  year: 1990
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0045
  publication-title: Jpn. J. Canc. Res.
  doi: 10.1111/j.1349-7006.1990.tb02559.x
– volume: 73
  start-page: 4385
  year: 2007
  ident: 10.1016/j.ijbiomac.2011.10.011_bib0150
  publication-title: Appl. Environm. Microbiol.
  doi: 10.1128/AEM.02470-06
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Snippet The main objective of the present study was to evaluate the antibacterial effect – through the determination of minimum inhibitory (and lethal) concentrations,...
The main objective of the present study was to evaluate the antibacterial effect - through the determination of minimum inhibitory (and lethal) concentrations,...
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SubjectTerms Anti-Bacterial Agents - chemistry
antibacterial properties
Atomic force microscopy
bacteria
Bifidobacterium - metabolism
Bifidobacterium animalis
carbon
Carbon - chemistry
cell biology
Chitin - chemistry
Chitooligosaccharides
Chitosan
Culture Media - chemistry
Glucose - chemistry
Hydrogen-Ion Concentration
Lactobacillus acidophilus
Lactobacillus acidophilus - metabolism
Microbial Sensitivity Tests
Microscopy, Atomic Force - methods
nutrient uptake
Oligosaccharides - chemistry
prebiotics
Probiotic bacteria
probiotics
Probiotics - metabolism
Time Factors
Title Evaluation of chitoligosaccharides effect upon probiotic bacteria
URI https://dx.doi.org/10.1016/j.ijbiomac.2011.10.011
https://www.ncbi.nlm.nih.gov/pubmed/22024313
https://www.proquest.com/docview/2000067194
https://www.proquest.com/docview/912107127
Volume 50
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