Pregnancy outcomes and ultrasonographic diagnosis in patients with histologically-proven placental chorioangioma

• Published in: Placenta (Eastbourne) Vol. 32; no. 9; pp. 671 - 674
• Main Authors: Wou, K, Chen, M.F, Mallozzi, A, Brown, R.N, Shrim, A
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.09.2011; Elsevier
• Subjects: Adult; Antenatal complications; Biological and medical sciences; Birth Weight; Chorioangioma; Embryology: invertebrates and vertebrates. Teratology; Female; Fundamental and applied biological sciences. Psychology; Hemangioma - diagnosis; Hemangioma - diagnostic imaging; Hemangioma - pathology; Humans; Infant, Low Birth Weight; Infant, Newborn; Intensive Care Units, Neonatal; Internal Medicine; Obstetrics and Gynecology; Placenta - diagnostic imaging; Placenta Diseases - diagnosis; Placenta Diseases - diagnostic imaging; Placenta Diseases - pathology; Placenta tumors; Pregnancy; Pregnancy Complications, Neoplastic - diagnostic imaging; Pregnancy Complications, Neoplastic - pathology; Pregnancy Outcome; Retrospective Studies; Ultrasonography, Prenatal; Ultrasound; Chorioangioma; Placenta tumors; Ultrasound; Antenatal complications; Human; Prognosis; Pregnancy disorders; Fetal membrane; Cardiovascular disease; Placenta diseases; Vascular disease; Pregnancy; Vertebrata; Mammalia; Placenta; Echography; Benign neoplasm; Diagnosis
• ISSN: 0143-4004; 1532-3102
• DOI: 10.1016/j.placenta.2011.06.007

Abstract Objective To evaluate pregnancy outcome and ultrasound diagnosis in patients with histologically-confirmed placental chorioangioma. Study design Placentas with histological diagnosis of chorioangioma were identified and medical charts were reviewed for findings of ultrasound examinations. Pregnancy outcomes were compared with all singleton deliveries without chorioangioma in the same time period. Main outcome measures Primary outcome was Neonatal Intensive Care Unit admission rate. Secondary outcome was ultrasound detection rate of chorioangioma. Results Among 14,725 singleton deliveries, 23 placentas were diagnosed with chorioangioma (0.16%). The control group included all singleton deliveries without chorioangioma ( n  = 14702). Neonates in the study group were more likely to be admitted to the Neonatal Intensive Care Unit (OR = 4.45) and to have smaller birth weight ( p  = 0.006). Only 2 of 7 larger chorioangiomas (≥2 cm) with available ultrasound reports were identified by ultrasound (29% detection rate). All cases demonstrated normal fetal growth and wellbeing. Conclusion Chorioangiomas are not always identified by routine prenatal sonography. Even in the absence of ultrasonic abnormalities, neonatal morbidity, as measured by NICU admission rate, is increased.