Metallothioneins and cadmium uptake by the liver in Bufo arenarum

Bufo arenarum females were treated daily with 0.5 mg Cd kg−1 during 10 days to evaluate the uptake of this heavy metal and the induction of metallothionein synthesis in the liver. The liver incorporated 26% of the Cd administered, about 6.5 times higher than the average uptake of the other tissues o...

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Published inEnvironmental pollution (1987) Vol. 97; no. 3; pp. 311 - 315
Main Authors Pérez-Coll, C.S., Herkovits, J., Fridman, O., Daniel, P., D'Eramo, J.L.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 1997
Elsevier
Subjects
Animal, plant and microbial ecology
Applied ecology
Biological and medical sciences
Bufo arenarum
Ecotoxicology, biological effects of pollution
Effects of pollution and side effects of pesticides on vertebrates
Freshwater
Fundamental and applied biological sciences. Psychology
Reptilia. Amphibia
South America
Argentina
America
Cadmium
Bufonidae
Liver
Amphibia
Detoxication
Salientia
Bufo arenarum
Experimental study
Uptake
Heavy metal
Vertebrata
Water pollution
Biological effect
Biological accumulation
Metallothionein
Xenobiotic
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Summary:Bufo arenarum females were treated daily with 0.5 mg Cd kg−1 during 10 days to evaluate the uptake of this heavy metal and the induction of metallothionein synthesis in the liver. The liver incorporated 26% of the Cd administered, about 6.5 times higher than the average uptake of the other tissues of B. arenarum. Three protein fractions from the B. arenarum liver bound Cd, and were induced by this xenobiotic up to approx. 24 times above the basal level of these proteins.
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ISSN:0269-7491
1873-6424
DOI:10.1016/S0269-7491(97)00071-7