Influence of altered maternal lipid profile on the lipid profile of the newborn

• Published in: Archives of Endocrinology and Metabolism Vol. 59; no. 2; pp. 123 - 128
• Main Authors: Sales, Willian B, Silleno Junior, J Dias, Kroll, Caroline, Mastroeni, Silmara S B S, Silva, Jean C, Mastroeni, Marco F
• Format: Journal Article
• Language: English
• Published: Brazil Brazilian Society of Endocrinology and Metabolism 01.04.2015
• Subjects: Adult; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Cross-Sectional Studies; Female; HDL-C; Humans; Infant, Newborn; LDL-C; Metabolome - physiology; Pregnancy; Total cholesterol; triglycerides; Triglycerides - blood; Weight Gain; Young Adult
• ISSN: 2359-3997; 2359-4292; 2359-4292; 2359-3997
• DOI: 10.1590/2359-3997000000024

To evaluate whether there is an association between altered maternal lipid profile and the lipid profile of the newborn in a maternity hospital. Cross-sectional study with 435 parturients and their respective newborns. Blood samples from the newborns were collected during delivery by venipuncture of the umbilical cord close to the placenta. Blood samples from the parturients were collected in the pre-delivery room or right after delivery. The concentrations of total cholesterol, triglycerides and HDL-c were determined by an enzymatic colorimetric method and LDL-c was calculated by the Friedewald formula. There was no significant difference in mean concentrations of total cholesterol, LDL-c, HDL-c and triglycerides in neonates according to altered or non-altered maternal total cholesterol, LDL-c, HDL-c and triglycerides. Change in maternal lipid profile is not significantly associated with the mean concentrations of total cholesterol, LDL-c, HDL-c and triglycerides in newborns.