Role of Hepatitis E Virus Infection in Acute-on-Chronic Liver Failure

• Published in: BioMed research international Vol. 2018; no. 2018; pp. 1 - 6
• Main Authors: Rivero-Juarez, Antonio, Rivero, Antonio, López-López, Pedro, Frias, Mario
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2018; Hindawi; Hindawi Limited
• Subjects: Acute-On-Chronic Liver Failure - virology; Alcohol; Chronic infection; Cirrhosis; Fibrosis; Hepatitis; Hepatitis E - complications; Hepatitis E virus; Hepatology; HIV; Human immunodeficiency virus; Humans; Infections; Liver; Liver cirrhosis; Liver Cirrhosis - virology; Liver diseases; Liver failure; Medical prognosis; Mortality; Patients; Review; Studies; Viruses; Bangladesh; Pakistan; Asia; United States > US; Gambia; China; France; Nepal; India
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2018/9098535

Chronic liver disease (CLD) with a variety of causes is currently reported to be one of the main causes of death worldwide. Patients with CLD experience deteriorating liver function and fibrosis, progressing to cirrhosis, chronic hepatic decompensation (CHD), end-stage liver disease (ESLD), and death. Patients may develop acute-on-chronic liver failure (ACLF), typically related to a precipitating event and associated with increased mortality. The objective of this review was to analyze the role of acute hepatitis E virus (HEV) infection in patients with CLD, focusing on the impact of this infection on patient survival and prognosis in several world regions.