Associations between chronic systemic diseases and primary open angle glaucoma: an epidemiological perspective

Glaucoma is a leading cause of global irreversible blindness. Primary open angle glaucoma (POAG) is the most common form of glaucoma and affects 44.1 million individuals worldwide. Elevation of intraocular pressure and impairment of vascular supply to the optic nerve head are two key pathogenic proc...

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Bibliographic Details
Published inClinical & experimental ophthalmology Vol. 45; no. 1; pp. 24 - 32
Main Authors Tham, Yih‐Chung, Cheng, Ching‐Yu
Format Journal Article
LanguageEnglish
Published Australia Wiley Subscription Services, Inc 01.01.2017
Subjects
Appointments & personnel changes
Chronic Disease - epidemiology
Diabetes
Glaucoma
Glaucoma, Open-Angle - epidemiology
Glaucoma, Open-Angle - etiology
Glaucoma, Open-Angle - physiopathology
Global Health
Humans
Hypertensive
Open angle glaucoma
Prevalence
Systemic diseases
Hypertensive
Open angle glaucoma
Diabetes
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Summary:Glaucoma is a leading cause of global irreversible blindness. Primary open angle glaucoma (POAG) is the most common form of glaucoma and affects 44.1 million individuals worldwide. Elevation of intraocular pressure and impairment of vascular supply to the optic nerve head are two key pathogenic processes in the development of POAG. In this regard, chronic systemic conditions such as hypertension, diabetes and obesity have been postulated to be correlated with these two pathogenic processes. Thus, it is plausible that chronic systemic diseases may act as risk factors for POAG. The aim of this review is to summarize the current evidence on the associations of chronic systemic diseases with POAG. These information will help to further ascertain the risk factors for POAG and improve the early detection of POAG.
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ISSN:1442-6404
1442-9071
DOI:10.1111/ceo.12763