Is propofol a safe agent in porphyria?

A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria. Urinary screening for porphyrins demonstrated a marked increase after this anaesthetic, but there were no clinical symptoms.

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Bibliographic Details
Published inAnaesthesia Vol. 43; no. 12; p. 1022
Main Authors Weir, P M, Hodkinson, B P
Format Journal Article
LanguageEnglish
Published England 01.12.1988
Subjects
Adult
Anesthesia, Intravenous
Anesthetics
Forearm Injuries - surgery
Humans
Liver Diseases - complications
Male
Phenols
Porphyrias - complications
Propofol
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Summary:A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria. Urinary screening for porphyrins demonstrated a marked increase after this anaesthetic, but there were no clinical symptoms.
ISSN:0003-2409
DOI:10.1111/j.1365-2044.1988.tb05699.x