What is the effect of ischemic preconditioning on the kinetics of pulmonary oxygen uptake and muscle deoxygenation during exercise?

• Published in: Physiological reports Vol. 3; no. 9; pp. e12540 - n/a
• Main Authors: Sabino‐Carvalho, Jeann L. C., Barbosa, Thales Coelho, Silva, Bruno Moreira
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.09.2015; John Wiley & Sons, Ltd
• Subjects: Blindness; Exercise; Infrared spectroscopy; Investigations; Ischemia; Letters to the Editor; Occlusion; Placebos; Spectrum analysis; Workloads
• ISSN: 2051-817X; 2051-817X
• DOI: 10.14814/phy2.12540

Specifically regarding the muscle deoxygenation, authors concluded that IPC accelerated its kinetics in the transition from low‐ to moderate‐intensity exercise, but did not change the kinetics in moderate‐ to severe‐intensity exercise. [...]the amplitude of the deoxy‐Hb/Mb response in the low‐ to moderate‐intensity exercise was reduced by IPC, whereas IPC did not change the amplitude in the moderate‐ to severe‐intensity exercise. Would the interpretation be similar if the analysis was done from data normalized by the resting baseline value or by the plateau during the 10‐min arterial occlusion? Besides Kido et al. ( ), two studies have also investigated the IPC effect on the balance between O2 utilization and delivery in the microcirculation via near‐infrared spectroscopy. More importantly, it is impossible to blind the subjects about the IPC exposure and all previous studies have not circumvented this problem properly (Salvador et al. ). [...]future studies should rigorously avoid the placebo effect on the investigation of the ergogenic effect of IPC (e.g., comparing the IPC with a placebo pill or other placebo interventions), since it may partially explain the reported improvement in exercise performance (Marocolo et al. ).