Cobalt-imidazole metal-organic framework loaded with luminol for paper-based chemiluminescence detection of catechol with use of a smartphone

• Published in: Analytical and bioanalytical chemistry Vol. 413; no. 13; pp. 3541 - 3550
• Main Authors: Li, Zimu, Xi, Yachao, Zhao, Anqi, Jiang, Jianming, Li, Bing, Yang, Xinming, He, Jianbo, Li, Fang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2021; Springer; Springer Nature B.V
• Subjects: Analysis; Analytical Chemistry; Biochemistry; Calibration; Catechin; Catechol; Characterization and Evaluation of Materials; Chemiluminescence; Chemistry; Chemistry and Materials Science; Cobalt; Composition; Drinking water; Emission; Food Science; Hydrogen peroxide; Identification and classification; Imidazole; Laboratory Medicine; Luminol; Metal-organic frameworks; Monitoring/Environmental Analysis; Morphology; Organometallic compounds; Properties; Reagents; Research Paper; Smart phones; Smartphones; Spectra; Tea; Water analysis; Water sampling; China; Chemiluminescence; Metal-organic framework; Catechol; Paper-based assay; Smartphone
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-021-03305-8

Chemiluminescence (CL) reagent luminol was loaded into the porous structure of cobalt-imidazole metal-organic framework (MOF) ZIF-67 to obtain luminol-functionalized ZIF-67 (luminol@ZIF-67) with CL property. The morphology, composition, CL property, and CL mechanism of luminol@ZIF-67 were carefully investigated. The obtained luminol@ZIF-67 exhibited strong, stable, and visible CL emission that reacted with H 2 O 2 , attributed to the strong catalytic effect of ZIF-67 combined with the shortened diffusion distance between luminol and the catalytic center. The CL intensity of luminol@ZIF-67 was more than 550 times higher than that of luminol. Catechol can effectively quench the CL emission of luminol@ZIF-67 that reacted with H 2 O 2 . Then, a simple paper-based CL imaging detection method was developed for the detection of catechol by using a smartphone as a portable detector. The linear calibration curve of the developed CL assay for catechol ranged from 5 to 100 mg/L with detection limit of 1.1 mg/L (S/N = 3δ). The strong CL emission of luminol@ZIF-67 combined with the effective quench ability of catechol guaranteed high sensitivity of the detection method. The practical application ability of the developed CL assay was tested by the determination of catechol in tea and tap water samples, resulting in acceptable results. This work provides an effective paper-based CL detection method for catechol and enriches the species of the chemiluminescent MOF material. Graphical abstract