Synthesis, characterization and antibacterial activity of some new pyrazole based Schiff bases

In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and...

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Published inArabian journal of chemistry Vol. 6; no. 3; pp. 335 - 340
Main Authors Malladi, Shridhar, Isloor, Arun M., Isloor, Shrikrishna, Akhila, D.S., Fun, Hoong-Kun
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.07.2013
Subjects
antibacterial properties
Antimicrobial activity
Bacillus subtilis
Escherichia coli
microorganisms
nuclear magnetic resonance spectroscopy
Pseudomonas aeruginosa
Pyrazoles
Schiff bases
Staphylococcus aureus
Triazoles
Schiff bases
Antimicrobial activity
Triazoles
Pyrazoles
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Summary:In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) activity. The results revealed that, compounds 3f and 3c have exhibited significant biological activity against the tested microorganisms.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2011.10.009