Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA...

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Bibliographic Details
Published inRheumatic diseases clinics of North America Vol. 44; no. 1; p. 89
Main Authors Craig, Ethan, Cappelli, Laura C
Format Journal Article
LanguageEnglish
Published United States 01.02.2018
Subjects
Antirheumatic Agents - pharmacology
Arthritis, Rheumatoid - drug therapy
Arthritis, Rheumatoid - immunology
Arthritis, Rheumatoid - physiopathology
Diagnosis, Differential
Gastrointestinal Diseases - diagnosis
Gastrointestinal Diseases - immunology
Gastrointestinal Tract - immunology
Gastrointestinal Tract - physiopathology
Humans
Liver Diseases - diagnosis
Liver Diseases - immunology
Hepatic disease
Antirheumatic medications (DMARDs)
Rheumatoid arthritis
Gastrointestinal disease
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Summary:Gastrointestinal (GI) manifestations of rheumatoid arthritis (RA) are rare, but can be impactful for patients. Some GI processes are directly related to RA, whereas others may be sequelae of treatment or caused by concomitant autoimmune diseases. This article discusses the role of the GI tract in RA pathogenesis; the presentation, epidemiology, and diagnosis of RA-related GI manifestations; concomitant GI autoimmune diseases that may affect those with RA; and GI side effects of RA treatment. The importance of appropriately considering conditions unrelated to RA in the differential diagnosis when evaluating new GI symptoms in patients with RA is noted.
ISSN:1558-3163
DOI:10.1016/j.rdc.2017.09.005