Immune-enhancing effects of polysaccharides MLN-1 from by-product of Mai-luo-ning in vivo and in vitro

In this study, a typical Chinese medicine injection (Mai-luo-ning, MLN) was chosen to study the transformation possibility of its by-products (polysaccharides). What's more, the basic properties of polysaccharides were also detected and its immunoprotect and anti-inflammatory activity were both...

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Bibliographic Details
Published inFood and agricultural immunology Vol. 30; no. 1; pp. 369 - 384
Main Authors Nie, Linfeng, Xiao, Qiuping, Liu, Shuangshuang, Li, Bo, Duan, Jinao, Fan, Yanhong, Guo, Liwei, He, Chenghua, Zhu, Huaxu
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis 01.01.2019
Taylor & Francis Ltd
Taylor & Francis Group
Subjects
Anti-inflammatory agents
Biocompatibility
By-product
Byproducts
Food additives
Herbal medicine
Immunoprotect
In vivo methods and tests
Inflammation
Lymphocytes
Mai-luo-ning
Polysaccharide
Polysaccharides
Saccharides
Toxicity
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Summary:In this study, a typical Chinese medicine injection (Mai-luo-ning, MLN) was chosen to study the transformation possibility of its by-products (polysaccharides). What's more, the basic properties of polysaccharides were also detected and its immunoprotect and anti-inflammatory activity were both proved in vivo and in vitro. The experiment determined that MLN-1 significantly increased the level of anti-inflammatory-related factors and the number of lymphocytes. Acute oral toxicity study established that MLN-1 has a non-toxic effect. The present work successfully showed that MLN-1 has the potential to be developed as a food additive.
ISSN:0954-0105
1465-3443
DOI:10.1080/09540105.2019.1582612