Ratiometric fluorescence for sensitive detection of phosphate species based on mixed lanthanide metal organic framework

• Published in: Analytical and bioanalytical chemistry Vol. 413; no. 12; pp. 3281 - 3290
• Main Authors: Li, Zhijian, Liu, Gang, Fan, Congbin, Pu, Shouzhi
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2021; Springer; Springer Nature B.V
• Subjects: Analysis; Analytical Chemistry; Aquatic ecosystems; Biochemistry; Cerium; Characterization and Evaluation of Materials; Chemical reactions; Chemical synthesis; Chemistry; Chemistry and Materials Science; Cooling; Ethanol; Fluorescence; Fluorescent indicators; Food Science; Hydrothermal reactions; Laboratories; Laboratory Medicine; Metal ions; Metal-organic frameworks; Methods; Monitoring/Environmental Analysis; Phosphates; Quantum dots; Rare earth metals; Research Paper; Stainless steel; Terbium; Terephthalic acid; China; Ratiometric fluorescence; Sensitive; Multiemission; Mixed lanthanide metal organic framework; Phosphate
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-021-03264-0

Phosphate (PO 4 3− ) plays a major role in aquatic ecosystems and biosystems. Developing a highly sensitive and selective ratiometric fluorescence probe for detection of PO 4 3− is of great significance to the ecological environment and human health. In this work, a novel dual lanthanide metal organic framework was synthesized via hydrothermal reaction based on Tb 3+ and Ce 3+ as the center metal ions and terephthalic acid as the organic ligand (designated as Tb-Ce-MOFs). The fluorescence of Tb-Ce-MOFs shows emission at 375 nm. In the presence of PO 4 3− , with increased concentration of PO 4 3− , the fluorescence intensity of Tb-Ce-MOFs at 500 nm and 550 nm increased, while the intensity at 375 nm was reduced. Hence, ratiometric fluorescence detecting of PO 4 3− can be achieved by measuring the ratio of fluorescence at 550 nm (FL 550 ) to 375 nm (FL 375 ) in the fluorescent spectra of the Tb-Ce-MOFs. In this sensing approach, the Tb-Ce-MOFs probe exhibits highly sensitive and selective for detection of PO 4 3− . The limit of detection is calculated to be 28 nM and the detection range is 0.1 to 10 μM. In addition, the Tb-Ce-MOFs were used in the detection of PO 4 3− in real samples. Graphical abstract We design and synthesize a mixed lanthanide metal organic framework fluorescence probe (Tb-Ce-MOFs) for ratiometric fluorescence for the detection of PO 4 3− based on Tb 3+ and Ce 3+ as the center metal ions and terephthalic acid as the organic ligand.