Inhibitors and promoters of stone formation

Currently, three main mechanisms are thought to be important in the formation of urinary stones: 1) the relationship between the concentration of the precipitating substances in urine and the solubility of the mineral phase formed, 2) the role of promoters of crystallization and aggregation, and 3)...

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Bibliographic Details
Published inKidney international Vol. 13; no. 5; pp. 361 - 371
Main Author Fleisch, Herbert
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.1978
Subjects
Animals
Calcium - antagonists & inhibitors
Calcium - urine
Calcium Phosphates - antagonists & inhibitors
Calcium Phosphates - urine
Crystallization
Diphosphonates - pharmacology
Humans
Oxalates - antagonists & inhibitors
Oxalates - urine
Proteinuria - complications
Urinary Calculi - etiology
Urinary Calculi - physiopathology
Urinary Calculi - urine
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Summary:Currently, three main mechanisms are thought to be important in the formation of urinary stones: 1) the relationship between the concentration of the precipitating substances in urine and the solubility of the mineral phase formed, 2) the role of promoters of crystallization and aggregation, and 3) the part played by inhibitors of crystal formation and aggregation (Fig. 1).
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0085-2538
1523-1755
DOI:10.1038/ki.1978.54