Work ability and work status changes in long-term Hodgkin lymphoma survivors with focus on late adverse effects

• Published in: Journal of cancer survivorship Vol. 18; no. 6; pp. 1921 - 1930
• Main Authors: Dahl, Alv A., Smeland, Knut B., Eikeland, Siri, Fagerli, Unn-Merete, Bersvendsen, Hanne S., Fosså, Alexander, Kiserud, Cecilie E.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2024; Springer Nature B.V
• Subjects: Adult; Cancer Survivors - psychology; Cancer Survivors - statistics & numerical data; Cross-Sectional Studies; Diagnosis; Disability pensions; Employment; Female; Health Informatics; Health Promotion and Disease Prevention; Hodgkin Disease - therapy; Hodgkin's lymphoma; Humans; Long Term Adverse Effects - epidemiology; Long Term Adverse Effects - etiology; Lymphoma; Male; Medicine; Medicine & Public Health; Mental disorders; Middle Aged; Oncology; Primary Care Medicine; Public Health; Quality of Life Research; Questionnaires; Side effects; Surveys; Surveys and Questionnaires; Cancer survivors; Late adverse effects; Work ability; Hodgkin lymphoma
• ISSN: 1932-2259; 1932-2267; 1932-2267
• DOI: 10.1007/s11764-023-01432-y

Purpose We studied work-related issues in long-term survivors of Hodgkin lymphoma [HLSs] who had undergone treatment according to contemporary stage risk-adapted approaches. At survey, work changes and problems since diagnosis, comparisons of HLSs with low/moderate versus high work ability, associations between work issues, and late adverse effects [LAEs] were examined. Methods This cross-sectional questionnaire-based study included HLSs treated from 1997 to 2006 and alive at the end of 2016. They completed a mailed questionnaire including work and health-related issues. Results Among 518 invited HLSs, 297 (58%) completed the work-related issues, and 48% of them were females. Mean age at survey was 45.9 years, and mean time was 16.7 years since diagnosis. At follow-up, 71% of the HLSs held paid work and 19% were on disability pension. Only 3% of HLSs did not hold paid work at any time after diagnosis. In total, 43% HLSs had low/moderate and 57% high work ability at follow-up. Low/moderate work ability was significantly associated with older age, female sex, more LAEs, disability pension, lower household income, distressed personality, obesity, fatigue, and mental disorders. More LAEs were significantly associated with more work problems. Conclusions Many HLSs manage to stay in the work force. Several health problems and LAEs amenable for interventions are significantly associated with low/moderate work ability and emphasize the importance of focus on these issues in long-term follow-up. Implications for Cancer Survivors HLSs in paid work at diagnosis can be optimistic as to their future participation in work life. Screening and treatment for health problems such as LAEs may improve work ability.