Plants and plant-based polymers as scaffolds for tissue engineering

Diverse scaffold materials created from a variety of biomaterials via a plethora of production methods have been applied to redevelop varied tissues and body organs. Irrespective of the tissue type, a number of factors such as biodegradability, biocompatibility, mechanical properties, scaffold archi...

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Published inGreen chemistry : an international journal and green chemistry resource : GC Vol. 21; no. 18; pp. 4839 - 4867
Main Authors Iravani, Siavash, Varma, Rajender S
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 2019
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Summary:Diverse scaffold materials created from a variety of biomaterials via a plethora of production methods have been applied to redevelop varied tissues and body organs. Irrespective of the tissue type, a number of factors such as biodegradability, biocompatibility, mechanical properties, scaffold architecture and manufacturing technology are important when designing or determining the suitability of a scaffold for usage in tissue engineering. The plant-based natural polymers, being derived from green and sustainable sources, meet the requirements for such novel biomaterials with desirable properties for tissue engineering that require minimal chemical processing for industrial applications. The significant advantage of plant scaffolds is the apparent ease with which they can be made and manipulated; they are quite pliable and can be easily cut, fashioned, rolled or stacked to form a range of different sizes and shapes. They are also renewable, easy to mass produce and are relatively inexpensive. This review describes the use of plants and plant-based polymers and highlights the collective roles of such biomaterials in the assembly of greener and natural-based scaffolds for tissue engineering. Plants and plant-based polymers used in the fabrication of greener scaffolds and their collective role for tissue engineering applications are highlighted.
Bibliography:Prof. Varma (H-Index 107; Highly Cited Researchers 2016-18; Publons Awardee 2018) was born in India (Ph.D., Delhi University 1976). After postdoctoral research at Robert Robinson Laboratories, Liverpool, U.K., he was faculty member at Baylor College of Medicine and Sam Houston State University prior to joining the Sustainable Technology Division at the US Environmental Protection Agency in 1999. He has a visiting scientist's position at Regional Centre of Advanced Technologies and Materials, Palacky University at Olomouc, Czech Republic. He has over 45 years of research experience in management of multidisciplinary technical programs ranging from natural products chemistry to development of more environmentally friendly synthetic methods using microwaves, ultrasound
Lately, he is focused on greener approaches to assembly of nanomaterials and sustainable applications of magnetically retrievable nanocatalysts in benign media. He is a member of the editorial advisory board of several international journals, has published over 535 papers, and has been awarded 16 US Patents, 6 books, 26 book chapters and 3 encyclopedia contributions with 37 800 citations.
Dr Iravani has worked on several academic research projects at the Isfahan University of Medical Sciences (Faculty of Pharmacy and Pharmaceutical Sciences), including green and eco-friendly synthesis of nanomaterials, plant-derived nanostructures, phytochemical analysis, graphene-based nanocomposites, water treatment technologies, nanoparticles for drug delivery in cancer, nanocarriers, and drug nanoparticles. His previous experience, of more than seven years, centers on drug development and industrial pharmacy in various capacities including research and development, formulation, and quality control. Dr Iravani has authored over 50 peer-reviewed scientific publications including twelve book chapters and one book.
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ISSN:1463-9262
1463-9270
DOI:10.1039/c9gc02391g