Transferable 20-Kilobase Multiple Drug Resistance-Conferring R Plasmid (pKL0018) from a Fish Pathogen (Lactococcus garvieae) Is Highly Homologous to a Conjugative Multiple Drug Resistance-Conferring Enterococcal Plasmid

• Published in: Applied and Environmental Microbiology Vol. 75; no. 10; pp. 3370 - 3372
• Main Authors: Maki, Takeshi, Santos, Mudjekeewis D, Kondo, Hidehiro, Hirono, Ikuo, Aoki, Takashi
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.05.2009; American Society for Microbiology (ASM)
• Subjects: Antibiotics; Bacteria; Biological and medical sciences; DNA, Bacterial - chemistry; DNA, Bacterial - genetics; Drug resistance; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecalis - drug effects; Enterococcus faecalis - genetics; Fundamental and applied biological sciences. Psychology; Gene Order; Genes; Genes, Bacterial; Lactococcus - drug effects; Lactococcus - genetics; Lactococcus garvieae; Meat products; Microbiology; Molecular Sequence Data; Plasmids; Public Health Microbiology; Sequence Analysis, DNA; Sequence Homology; Synteny; Plasmid; Streptococcaceae; Lactic acid bacteria; Vertebrata; Lactococcus; Pathogenic; Pisces; Multiple resistance; Bacteria; Micrococcales
• ISSN: 0099-2240; 1098-5336; 1098-6596
• DOI: 10.1128/AEM.00039-09

Lactococcus garvieae, the causative agent of lactococcosis, has evolved strains that are highly resistant to antibiotics. Here, the 20,034-bp sequence of L. garvieae conjugative plasmid pKL0018 was determined. It contained two ermB genes and one tetS gene and a backbone more than 96% identical to that of pRE25, an Enterococcus faecalis plasmid from dry sausage.