Parotid Gland Biopsy, the Alternative Way to Diagnose Sjögren Syndrome

Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjögren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis, amyloidosis). In SS characteristic histology findings are found, including lymphocytic infiltration surrounding the excretory ducts in combin...

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Bibliographic Details
Published inRheumatic diseases clinics of North America Vol. 42; no. 3; p. 485
Main Authors Spijkervet, Fred K L, Haacke, Erlin, Kroese, Frans G M, Bootsma, Hendrika, Vissink, Arjan
Format Journal Article
LanguageEnglish
Published United States 01.08.2016
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Summary:Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjögren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis, amyloidosis). In SS characteristic histology findings are found, including lymphocytic infiltration surrounding the excretory ducts in combination with destruction of acinar tissue. In this article the main techniques are described for taking labial and parotid salivary gland biopsies with respect to their advantages, postoperative complications, and usefulness for diagnostic procedures, monitoring disease progression, and evaluation of treatment.
ISSN:1558-3163
DOI:10.1016/j.rdc.2016.03.007