Progress in Copper-Mediated Formation of Trifluoromethylated Arenes

Development of transition‐metal‐catalyzed trifluoromethylation of arene substrates under mild reaction conditions has attracted great attention in the past few years. Among the many methods developed, copper‐mediated trifluororomethylation has made significant progress and is the subject of this min...

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Bibliographic Details
Published inEuropean journal of organic chemistry Vol. 2012; no. 34; pp. 6679 - 6687
Main Authors Liu, Tianfei, Shen, Qilong
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 01.12.2012
WILEY‐VCH Verlag
Wiley-VCH
Wiley Subscription Services, Inc
Subjects
Arenes
Chemistry
Copper
Exact sciences and technology
Fluorine
Noncondensed benzenic compounds
Organic chemistry
Preparations and properties
Trifluoromethylation
Arene
Catalytic reaction
Copper ion
Trifluoromethylation
Mild operating conditions
Fluorine
Arenes
Aromatic compound
Transition metal
Copper
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Summary:Development of transition‐metal‐catalyzed trifluoromethylation of arene substrates under mild reaction conditions has attracted great attention in the past few years. Among the many methods developed, copper‐mediated trifluororomethylation has made significant progress and is the subject of this minireview. Recent advances in copper‐mediated trifluoromethylation of arene substrates are reviewed.
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SourceType-Scholarly Journals-1
content type line 14
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201200648