Gualamycin, a Novel Acaricide Produced by Streptomyces sp. NK11687 I. Taxonomy, Production, Isolation, and Preliminary Characterization

A novel acaricide, gualamycin, was isolated from the culture broth of Streptomyces sp. NK11687. It was purified from the filtrate by column chromatographies. Gualamycin showed 100% acaricidal activity at 250 μg/ml against sensitive and resistant mites to Dicofol.

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Bibliographic Details
Published inJournal of antibiotics Vol. 48; no. 7; pp. 626 - 629
Main Authors TSUCHIYA, KOUICHI, KOBAYASHI, SFFINICHI, HARADA, TAKASHI, KUROKAWA, TAKASHI, NAKAGAWA, TAIZO, SHIMADA, NOBUYOSHI, KOBAYASHI, KENJI
Format Journal Article
LanguageEnglish
Published Tokyo JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 1995
Japan Antibiotics Research Association
Subjects
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
Biological and medical sciences
Disaccharides - chemistry
Disaccharides - isolation & purification
Disaccharides - pharmacology
Female
Fermentation
Insecticides - chemistry
Insecticides - isolation & purification
Insecticides - pharmacology
Medical sciences
Mites - drug effects
Molecular Structure
Pharmacology. Drug treatments
Pyrrolidines - chemistry
Pyrrolidines - isolation & purification
Pyrrolidines - pharmacology
Streptomyces
Actinomycetales
Characterization
Acaricide
Streptomycetaceae
Production
Streptomyces
Bacteria
Isolation
Actinomycetes
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Summary:A novel acaricide, gualamycin, was isolated from the culture broth of Streptomyces sp. NK11687. It was purified from the filtrate by column chromatographies. Gualamycin showed 100% acaricidal activity at 250 μg/ml against sensitive and resistant mites to Dicofol.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.48.626