A compact respiratory-triggering device for routine microimaging of laboratory mice

A partial-body plethysmograph was developed for measuring the respiratory flow of anesthetized mice during routine microimaging experiments performed in the close confines of an 89-mm-diameter, vertical-bore magnet. Respiratory flow patterns were used for synchronizing conventional T2-weighted spin-...

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Bibliographic Details
Published inJournal of magnetic resonance imaging Vol. 8; no. 6; p. 1343
Main Authors Minard, K R, Wind, R A, Phelps, R L
Format Journal Article
LanguageEnglish
Published United States 01.11.1998
Subjects
Animals
Equipment Design
Liver - pathology
Liver Neoplasms, Experimental - diagnosis
Magnetic Resonance Imaging - instrumentation
Male
Mice
Plethysmography - instrumentation
Respiration
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Summary:A partial-body plethysmograph was developed for measuring the respiratory flow of anesthetized mice during routine microimaging experiments performed in the close confines of an 89-mm-diameter, vertical-bore magnet. Respiratory flow patterns were used for synchronizing conventional T2-weighted spin-echo imaging with the respiratory cycle, thereby, significantly reducing motion-induced artifacts and increasing observed liver lesion contrast.
ISSN:1053-1807
DOI:10.1002/jmri.1880080626