DNA Microarray Technology in Microbial Ecology Studies-Principle, Applications and Current Limitations

DNA microarray technology has been successfully used in numerous medical and clinical applications, but its application in environmental studies for bacterial detection and microbial community analysis has faced many challenges due to the highly diverse and complex nature of environmental samples. O...

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Bibliographic Details
Published inMicrobes and Environments Vol. 18; no. 4; pp. 175 - 187
Main Authors Li, Emily S.Y., Liu, Wen-Tso
Format Journal Article
LanguageEnglish
Published Miyagi Japanese Society of Microbial Ecology / Japanese Society of Soil Microbiology / Taiwan Society of Microbial Ecology / Japanese Society of Plant Microbe Interactions / Japanese Society for Extremophiles 2003
Japan Science and Technology Agency
Subjects
DNA microarray
hybridization
microbial diversity
microbial ecology
microchip
rRNA
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Summary:DNA microarray technology has been successfully used in numerous medical and clinical applications, but its application in environmental studies for bacterial detection and microbial community analysis has faced many challenges due to the highly diverse and complex nature of environmental samples. Only a limited number of studies have been published, mainly showing the "proof of principle" of the method in this field of research. More rigorous and systematic assessments and improvements are required to extend the microarray technique to its full potential. Here, some fundamental concepts involved in the microarray technique are discussed, and recent developments in microarray-based technology in microbial ecology applications are reviewed.
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ISSN:1342-6311
1347-4405
DOI:10.1264/jsme2.18.175