Anaesthetic management of glucagonoma

Alpha cell tumours of the pancreatic islets of Langerhans are rare. The glucagonoma syndrome is caused by excess glucagon secretion from such a tumour. Physiologically, glucagon is important in the control of the homeostatis of glucose and certain amino acids. Pharmacologically, it has been used to...

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Bibliographic Details
Published inAnaesthesia Vol. 40; no. 2; p. 152
Main Authors Nicoll, J M, Catling, S J
Format Journal Article
LanguageEnglish
Published England 01.02.1985
Subjects
Adenoma, Islet Cell - surgery
Adult
Anesthesia, General
Blood Glucose - analysis
Female
Glucagon - blood
Glucagonoma - surgery
Humans
Intraoperative Period
Pancreatic Neoplasms - surgery
Pancreatic Polypeptide - blood
Postoperative Period
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Summary:Alpha cell tumours of the pancreatic islets of Langerhans are rare. The glucagonoma syndrome is caused by excess glucagon secretion from such a tumour. Physiologically, glucagon is important in the control of the homeostatis of glucose and certain amino acids. Pharmacologically, it has been used to treat heart failure. Problems with both glucose homeostasis and myocardial function could, therefore, theoretically be anticipated following resection of a glucagonoma. This paper describes the peri-operative management of such a case, where, despite measured changes in glucagon, no problems of this nature were encountered.
ISSN:0003-2409
DOI:10.1111/j.1365-2044.1985.tb10706.x