Sclerosing hemangioma, presenting as a pneumonic pattern with mucinous adenomatous hyperplasia of the lung

• Published in: Pathology international Vol. 58; no. 11; pp. 735 - 740
• Main Authors: Choi, Keum H., Baek, Hyun A., Park, Ho S., Jang, Kyu Y., Jin, Gong‐Yong, Kim, Min H., Lee, Yong C., Moon, Woo S., Chung, Myoung‐Ja
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.11.2008
• Subjects: Adenoma - chemistry; Adenoma - pathology; Adenoma - surgery; Biomarkers, Tumor - analysis; Diagnosis, Differential; Female; Humans; Hyperplasia; Immunoenzyme Techniques; Middle Aged; mucinous adenomatous hyperplasia; Nuclear Proteins - analysis; Pneumonia - pathology; Pulmonary Sclerosing Hemangioma - chemistry; Pulmonary Sclerosing Hemangioma - pathology; Pulmonary Sclerosing Hemangioma - surgery; pulmonary sclerosing hemangioma with pneumonic pattern; Radiography, Thoracic; Thyroid Nuclear Factor 1; Transcription Factors - analysis
• ISSN: 1320-5463; 1440-1827
• DOI: 10.1111/j.1440-1827.2008.02302.x

Pulmonary sclerosing hemangioma is generally considered a rare neoplasm presenting as a solitary benign nodule. During routine medical examination multiple abnormal nodular shadows were detected in the right lower lung field on chest X‐ray in a 48‐year‐old asymptomatic woman. The patient underwent wedge resection for the pulmonary lesion. The resected lung had numerous scattered tiny nodules and small nodules congregated together, forming larger nodules. All of these lesions had typical features of sclerosing hemangioma. The authors call this unusual growth pattern of sclerosing hemangioma a ‘pneumonic pattern’. Adjacent to the largest lesion, a relatively well‐defined small mucinous lesion composed of mucinous tall columnar cells and basaloid squamous cells was detected. Because this lesion did not have expression of thyroid transcription factor‐1, it is described as mucinous adenomatous hyperplasia.