Epidural diamorphine and bupivacaine in labour

A double-blind randomised study was performed to assess the analgesic effect of epidural diamorphine, administered with bupivacaine, on primigravid women in labour. Fifty patients received 0.25% bupivacaine 10 ml via the epidural catheter as their initial dose; patients in Group 1 received diamorphi...

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Bibliographic Details
Published inAnaesthesia Vol. 44; no. 5; p. 400
Main Authors McGrady, E M, Brownhill, D K, Davis, A G
Format Journal Article
LanguageEnglish
Published England 01.05.1989
Subjects
Analgesia, Epidural
Anesthesia, Obstetrical
Bupivacaine - administration & dosage
Bupivacaine - adverse effects
Clinical Trials as Topic
Double-Blind Method
Female
Heroin - administration & dosage
Heroin - adverse effects
Humans
Labor, Obstetric
Pregnancy
Random Allocation
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Summary:A double-blind randomised study was performed to assess the analgesic effect of epidural diamorphine, administered with bupivacaine, on primigravid women in labour. Fifty patients received 0.25% bupivacaine 10 ml via the epidural catheter as their initial dose; patients in Group 1 received diamorphine 5 mg with the bupivacaine. A 0.1% bupivacaine infusion was started at 10 minutes and bolus doses of bupivacaine were given if required. There was a significant reduction in rate of bupivacaine administration, pain scores at 20 and 30 minutes, number of supplements required, and degree of motor blockade in the diamorphine group.
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.1989.tb11338.x