Colour M-mode velocity propagation: a glance at intra-ventricular pressure gradients and early diastolic ventricular performance
The physiology of early‐diastolic filling comprises ventricular performance and fluid dynamical principles. Elastic recoil and myocardial relaxation rate determine left ventricular early diastolic performance. The integrity of left ventricular synchrony and geometry is essential to maintain the effe...
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Published in | European journal of heart failure Vol. 7; no. 1; pp. 19 - 28 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Blackwell Publishing Ltd
01.01.2005
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Subjects | |
Online Access | Get full text |
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Summary: | The physiology of early‐diastolic filling comprises ventricular performance and fluid dynamical principles. Elastic recoil and myocardial relaxation rate determine left ventricular early diastolic performance. The integrity of left ventricular synchrony and geometry is essential to maintain the effect of their timely action on early diastolic left ventricular filling. These factors not only are prime determinants of left ventricular pressure decay during isovolumic relaxation and immediately after mitral valve opening; they also instigate the generation of a sufficient intra‐ventricular pressure gradient, which enhances efficient early diastolic left ventricular filling. Accurate assessment of diastolic (dys)function by non‐invasive techniques has important therapeutic and prognostic implications but remains a challenge to the cardiologist. The evaluation of left ventricular relaxation by the standard Doppler echocardiographic parameters is hindered by their preload dependency. The colour M‐mode velocity propagation of early diastolic inflow (Vp) correlates with intra‐ventricular pressure gradients and is a largely preload independent index of ventricular diastolic performance. In this article, the physiologic background, utility and limitations of this promising new tool for the study of early diastolic filling are reviewed. |
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Bibliography: | ArticleID:EJHF2004-03-010 istex:EA79CBA429386CA951E9C29E7AAFB25695E6561D ark:/67375/WNG-6TJ818V3-H ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 1388-9842 1879-0844 |
DOI: | 10.1016/j.ejheart.2004.03.010 |