Optical tractography of the mouse heart using polarization-sensitive optical coherence tomography

We developed a method to image myocardial fiber architecture in the mouse heart using a Jones matrix-based polarization-sensitive optical coherence tomography (PSOCT) system. The "cross-helical" laminar structure of myocardial fibers can be clearly visualized using this technology. The obt...

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Bibliographic Details
Published inBiomedical optics express Vol. 4; no. 11; pp. 2540 - 2545
Main Authors Wang, Yuanbo, Yao, Gang
Format Journal Article
LanguageEnglish
Published United States Optical Society of America 01.11.2013
Subjects
Optical Coherence Tomography
(110.4500) Optical coherence tomography
(230.5440) Polarization
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Summary:We developed a method to image myocardial fiber architecture in the mouse heart using a Jones matrix-based polarization-sensitive optical coherence tomography (PSOCT) system. The "cross-helical" laminar structure of myocardial fibers can be clearly visualized using this technology. The obtained myocardial fiber organization agrees well with existing knowledge acquired using conventional histology and diffusion tensor magnetic resonance imaging.
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ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.4.002540