The Problem of Carbapenemase-Producing-Carbapenem-Resistant-Enterobacteriaceae Detection

The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) are a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE de...

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Published inJournal of clinical microbiology Vol. 54; no. 3; pp. 529 - 534
Main Authors Lutgring, Joseph D, Limbago, Brandi M
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.03.2016
Subjects
Anti-Bacterial Agents - pharmacology
Bacterial Proteins - analysis
Bacteriological Techniques - methods
beta-Lactam Resistance
beta-Lactamases - analysis
Carbapenems - pharmacology
Diagnostic Tests, Routine - methods
Enterobacteriaceae - enzymology
Enterobacteriaceae - isolation & purification
Enterobacteriaceae Infections - diagnosis
Enterobacteriaceae Infections - microbiology
Humans
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Summary:The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) are a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE detection. There is no single detection method that is ideal for all situations.
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Citation Lutgring JD, Limbago BM. 2016. The problem of carbapenemase-producing-carbapenem-resistant-Enterobacteriaceae detection. J Clin Microbiol 54:529–534. doi:10.1128/JCM.02771-15.
ISSN:0095-1137
1098-660X
DOI:10.1128/jcm.02771-15