Tantalum-coated polylactic acid fibrous membranes for guided bone regeneration

• Published in: Materials Science & Engineering C Vol. 115; p. 111112
• Main Authors: Hwang, Changha, Park, Suhyung, Kang, In-Gu, Kim, Hyoun-Ee, Han, Cheol-Min
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2020; Elsevier BV
• Subjects: Animals; Biocompatibility; Biocompatible Materials - chemistry; Biocompatible Materials - pharmacology; Biodegradability; Biodegradation; Biomedical materials; Bone growth; Bone healing; Bone Regeneration - drug effects; Cell Differentiation - drug effects; Cell Line; Cell Proliferation - drug effects; Chemical composition; Coating; Coatings; Collagen; Defects; Electrospinning; Fibers; Fibrous structure; Guided bone regeneration; Guided Tissue Regeneration - instrumentation; Healing; In vivo methods and tests; Male; Materials science; Mechanical properties; Membranes; Membranes, Artificial; Mice; Nanofibers; Osteoblasts - cytology; Osteoblasts - drug effects; Osteoconduction; Polyesters - chemistry; Polylactic acid; Rabbits; Regeneration; Regeneration (physiology); Soft tissues; Sputtering; Tantalum; Tantalum - chemistry; Tantalum - pharmacology; X-Ray Microtomography; Electrospinning; Tantalum; Guided bone regeneration; Sputtering; Polylactic acid

Guided bone regeneration (GBR) membrane is necessary to reconstruct the defect bone tissue by defending penetration of soft tissues. Polylactic acid (PLA) attracts much attention to utilize as a GBR membrane because it has relatively high mechanical strength and biodegradability. However, the poor o...