In-vivo multilaboratory investigation of the optical properties of the human head

• Published in: Biomedical optics express Vol. 6; no. 7; pp. 2609 - 2623
• Main Authors: Farina, Andrea, Torricelli, Alessandro, Bargigia, Ilaria, Spinelli, Lorenzo, Cubeddu, Rinaldo, Foschum, Florian, Jäger, Marion, Simon, Emanuel, Fugger, Oliver, Kienle, Alwin, Martelli, Fabrizio, Di Ninni, Paola, Zaccanti, Giovanni, Milej, Daniel, Sawosz, Piotr, Kacprzak, Michał, Liebert, Adam, Pifferi, Antonio
• Format: Journal Article
• Language: English
• Published: United States Optical Society of America 01.07.2015
• Subjects: (170.5280) Photon migration; (170.6935) Tissue characterization; (170.3660) Light propagation in tissues; (300.0300) Spectroscopy
• ISSN: 2156-7085; 2156-7085
• DOI: 10.1364/BOE.6.002609

The in-vivo optical properties of the human head are investigated in the 600-1100 nm range on different subjects using continuous wave and time domain diffuse optical spectroscopy. The work was performed in collaboration with different research groups and the different techniques were applied to the same subject. Data analysis was carried out using homogeneous and layered models and final results were also confirmed by Monte Carlo simulations. The depth sensitivity of each technique was investigated and related to the probed region of the cerebral tissue. This work, based on different validated instruments, is a contribution to fill the existing gap between the present knowledge and the actual in-vivo values of the head optical properties.