Complexities of Viral Mutation Rates

Many viruses evolve rapidly. This is due, in part, to their high mutation rates. Mutation rate estimates for over 25 viruses are currently available. Here, we review the population genetics of virus mutation rates. We specifically cover the topics of mutation rate estimation, the forces that drive t...

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Bibliographic Details
Published inJournal of virology Vol. 92; no. 14
Main Authors Peck, Kayla M., Lauring, Adam S.
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 15.07.2018
Subjects
Evolution, Molecular
Gem
Humans
Mutation
Mutation Rate
Virus Replication
Viruses - genetics
mutation rate evolution
polymerase fidelity
polymerase
viral mutation rates
virus evolution
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Summary:Many viruses evolve rapidly. This is due, in part, to their high mutation rates. Mutation rate estimates for over 25 viruses are currently available. Here, we review the population genetics of virus mutation rates. We specifically cover the topics of mutation rate estimation, the forces that drive the evolution of mutation rates, and how the optimal mutation rate can be context-dependent.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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Citation Peck KM, Lauring AS. 2018. Complexities of viral mutation rates. J Virol 92:e01031-17. https://doi.org/10.1128/JVI.01031-17.
ISSN:0022-538X
1098-5514
1098-5514
DOI:10.1128/JVI.01031-17