Nocardia asteroides keratitis presenting as a persistent epithelial defect

An elderly male presented with epithelial defect which resisted all medical and therapeutic approaches until Gram stain and cultural report documented the presence of Nocardia asteroides of the offending organism. A 3-month course of chronic keratitis with persistent epithelial defect resolved in 48...

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Bibliographic Details
Published inCornea Vol. 8; no. 1; p. 41
Main Authors Perry, H D, Nauheim, J S, Donnenfeld, E D
Format Journal Article
LanguageEnglish
Published United States 1989
Subjects
Aged
Bacteriological Techniques
Cornea - pathology
Drug Combinations - administration & dosage
Epithelium - pathology
Humans
Infusions, Intravenous
Keratitis - drug therapy
Keratitis - microbiology
Keratitis - pathology
Male
Nocardia asteroides - ultrastructure
Nocardia Infections - drug therapy
Nocardia Infections - microbiology
Nocardia Infections - pathology
Sulfamethoxazole - administration & dosage
Trimethoprim - administration & dosage
Trimethoprim, Sulfamethoxazole Drug Combination
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Summary:An elderly male presented with epithelial defect which resisted all medical and therapeutic approaches until Gram stain and cultural report documented the presence of Nocardia asteroides of the offending organism. A 3-month course of chronic keratitis with persistent epithelial defect resolved in 48 h following the use of topical trimethoprim-sulfamethoxazole.
ISSN:0277-3740
DOI:10.1097/00003226-198903000-00007