Resveratrol Role in Autoimmune Disease-A Mini-Review

• Published in: Nutrients Vol. 9; no. 12; p. 1306
• Main Authors: Oliveira, Ana Lígia de Brito, Monteiro, Valter Vinicius Silva, Navegantes-Lima, Kely Campos, Reis, Jordano Ferreira, Gomes, Rafaelli de Souza, Rodrigues, Dávila Valentina Silva, Gaspar, Silvia Letícia de França, Monteiro, Marta Chagas
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.12.2017; MDPI
• Subjects: Animals; Antioxidants; Arthritis; Autoimmune diseases; Autoimmune Diseases - drug therapy; autoimmunity; Beverages; Chronic conditions; Diabetes mellitus; Diabetes mellitus (insulin dependent); Grapes; Humans; inflammation; Inflammatory bowel diseases; Intestine; Molecular Structure; organ-specific; Psoriasis; Resveratrol; Review; Rheumatoid arthritis; Stilbenes - chemistry; Stilbenes - therapeutic use; systemic; Systemic lupus erythematosus; Wines; systemic; autoimmunity; inflammation; resveratrol; organ-specific
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu9121306

Autoimmune diseases are still considered to be pressing concerns due the fact that they are leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a variety of foods and beverages, including red grapes and red wine. Anti-inflammatory, antioxidant, and antiaging properties of resveratrol have been reported, and in some animal and human studies this compound reduced and ameliorated the progression of autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and type 1 diabetes mellitus. Thus, this review aims to summarize and critically analyze the role of resveratrol in the modulation of several organ-specific or systemic autoimmune diseases.