Demonstration of uniformity of calcium absorption in adult dogs and cats

• Published in: Journal of animal physiology and animal nutrition Vol. 99; no. 5; pp. 801 - 809
• Main Authors: Mack, J. K, Alexander, L. G, Morris, P. J, Dobenecker, B, Kienzle, E
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Science 01.10.2015; Blackwell Publishing Ltd; Wiley Subscription Services, Inc
• Subjects: absorption; adults; Aging; Animal Feed - analysis; Animals; calcium; Calcium - pharmacokinetics; cats; Cats - physiology; digestibility; digestion; dogs; Dogs - physiology; excretion; food intake; meta-analysis; mineral metabolism; Minerals - pharmacokinetics; nutrition; phosphorus; Phosphorus - pharmacokinetics; regression analysis; small animal; true digestibility; nutrition; true digestibility; mineral metabolism; small animal; phosphorus
• ISSN: 0931-2439; 1439-0396
• DOI: 10.1111/jpn.12294

A meta‐analysis was conducted to understand quantitative aspects of calcium (Ca) and phosphorus (P) absorption in adult dogs and cats. 34 studies in dogs and 14 studies in cats met the criteria for inclusion in the meta‐analysis. Intake and faecal excretion values of Ca and P were subjected to a modified Lucas test and subsequent regression analyses. According to the current scientific consensus, Ca true digestibility (absorption) should increase at low Ca intake and decrease at high Ca intake. If true, this should result in a nonlinear relationship between the percentage of Ca excreted and dietary Ca intake. The present meta‐analysis showed a highly significant linear relationship (p < 0.0001) between Ca intake and Ca excretion suggesting a lack of systematic quantitative adaptation in true Ca digestibility. This finding suggests either that the time period covered by standard digestion trials is too short to induce adaptation mechanisms or that dogs and cats at maintenance will not efficiently alter quantitative Ca absorption percentage according to the amount ingested. If the latter is true, a dietary Ca supply differing greatly from the recommended dietary intake might impair the health of cats and dogs when fed long term. The data plots for P intake and faecal excretion were less uniform suggesting other factors not just dietary intake influence faecal P excretion. In adult cats, the dietary Ca:P ratio strongly influenced the true digestibility of P, whereas this effect was less marked in adult dogs. Faecal P excretion was significantly correlated to faecal Ca excretion in both species (p < 0.0001), and surprisingly, the level of P intake did not appear to be an important determinant of true digestibility of P.