Coronal Three-Dimensional Magnetic Resonance Imaging for Improving Diagnostic Accuracy for Posterior Ligamentous Complex Disruption In a Goat Spine Injury Model

• Published in: Korean journal of radiology Vol. 20; no. 4; pp. 641 - 648
• Main Authors: Zhu, Xuee, Wang, Jichen, Zhou, Dan, Feng, Chong, Dong, Zhiwen, Yu, Hanxiao
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Radiology 01.04.2019; 대한영상의학회
• Subjects: Accuracy; Animals; Contusions; Disease Models, Animal; Dissection; Female; Goats; Imaging, Three-Dimensional; Joint and ligament injuries; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Musculoskeletal Imaging; Reproducibility of Results; Sensitivity and Specificity; Spinal Injuries - diagnosis; Spinal Injuries - diagnostic imaging; Spine - diagnostic imaging; 방사선과학; United States > US; Animal model; MRI; Spine; Trauma
• ISSN: 1229-6929; 2005-8330; 2005-8330
• DOI: 10.3348/kjr.2018.0632

The purpose of this study was to investigate whether three-dimensional (3D) magnetic resonance imaging could improve diagnostic accuracy for suspected posterior ligamentous complex (PLC) disruption. We used 20 freshly harvested goat spine samples with 60 segments and intact surrounding soft tissue. The animals were aged 1-1.5 years and consisted of 8 males and 12 females, which were sexually mature but had not reached adult weights. We created a paraspinal contusion model by percutaneously injecting 10 mL saline into each side of the interspinous ligament (ISL). All segments underwent T2-weighted sagittal and coronal short inversion time inversion recovery (STIR) scans as well as coronal and sagittal 3D proton density-weighted spectrally selective inversion recovery (3D-PDW-SPIR) scans acquired at 1.5T. Following scanning, some ISLs were cut and then the segments were re-scanned using the same magnetic resonance (MR) techniques. Two radiologists independently assessed the MR images, and the reliability of ISL tear interpretation was assessed using the kappa coefficient. The chi-square test was used to compare the diagnostic accuracy of images obtained using the different MR techniques. The interobserver reliability for detecting ISL disruption was high for all imaging techniques (0.776-0.949). The sensitivity, specificity, and diagnostic accuracy of the coronal 3D-PDW-SPIR technique for detecting ISL tears were 100, 96.9, and 97.9%, respectively, which were significantly higher than those of the sagittal STIR ( = 0.000), coronal STIR ( = 0.000), and sagittal 3D-PDW-SPIR ( = 0.001) techniques. Compared to other MR methods, coronal 3D-PDW-SPIR provides a more accurate diagnosis of ISL disruption. Adding coronal 3D-PDW-SPIR to a routine MR protocol may help to identify PLC disruptions in cases with nearby contusion.