Fabrication of terazocin-loaded poly(D,L-lactide) microspheres by an ultrasonic spray drying method and their release behaviors

• Published in: Journal of nanoscience and nanotechnology Vol. 8; no. 10; p. 5139
• Main Authors: An, Guk-Hwan, Kim, Min-Jung, Lee, Hak-Jong, Park, Sang-Soo, Cho, Yong Woo, Park, Kinam, Choa, Yong-Ho
• Format: Journal Article
• Language: English
• Published: United States 01.10.2008
• Subjects: Microscopy, Electron, Scanning; Polyesters - chemistry; Prazosin - analogs & derivatives; Prazosin - chemistry; Spectroscopy, Fourier Transform Infrared; Ultrasonics

Terazocin should be frequently administered for a long period time for the treatment of benign prostatic hyperplasia which is one of the most common diseases in elderly men. Controlled delivery of terazocin using polymer microspheres has a great potential to solve the problem. In this study, terazoc...