In vitro simulation and quantification of wear within the patellofemoral joint replacement

Abstract Quantification of the wear rate in vitro is now considered an essential step in the development of a new joint replacement prior to clinical trials. However, little research exists around in vitro simulation of wear in the patellofemoral joint (PFJ) despite over 200,000 being implanted annu...

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Bibliographic Details
Published inJournal of biomechanics Vol. 41; no. 7; pp. 1407 - 1416
Main Authors Ellison, P, Barton, D.C, Esler, C, Shaw, D.L, Stone, M.H, Fisher, J
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.01.2008
Elsevier Limited
Subjects
Arthroplasty, Replacement, Knee - economics
Arthroplasty, Replacement, Knee - methods
Design
European Union
Femur - physiology
Humans
Knee
Knee Joint - physiology
Knee Prosthesis - economics
Materials Testing - methods
Models, Biological
Patella
Patella - physiology
Physical Medicine and Rehabilitation
Polymethyl methacrylate
Prostheses
Replacement
Studies
Wear
United Kingdom > UK
Knee
Replacement
Patella
Wear
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Summary:Abstract Quantification of the wear rate in vitro is now considered an essential step in the development of a new joint replacement prior to clinical trials. However, little research exists around in vitro simulation of wear in the patellofemoral joint (PFJ) despite over 200,000 being implanted annually within the European Union. A method to simulate wear in the laboratory using four input degrees of freedom within the PFJ of total knee replacement (TKR) has been developed. Wear simulation was validated through comparison of functional kinematics and patellar surface damage modes produced in vitro to clinical outcomes. The technique has been shown to replicate the prescribed in vivo kinematics in a reproducible and repeatable manner. The wear scar areas were similar to those found in vivo. However, geometrical measurements of wear were not reliable due to creep and geometry changes. As has been found previously with tibial inserts, geometrical determination of wear volume was not found to be an effective method of comparing wear from simulators and retrievals. Change in volume calculated gravimetrically was seen to be the most repeatable measure of patellar wear in vitro.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0021-9290
1873-2380
DOI:10.1016/j.jbiomech.2008.02.029