Preliminary Investigation about Aspergillus spp. Spread in Umbrian Avian Farms

• Published in: Journal of fungi (Basel) Vol. 8; no. 11; p. 1213
• Main Authors: Cruciani, Deborah, Crotti, Silvia, Maresca, Carmen, Pecorelli, Ivan, Verdini, Emanuela, Rodolfi, Marinella, Scoccia, Eleonora, Spina, Sara, Valentini, Andrea, Agnetti, Francesco
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 16.11.2022; MDPI
• Subjects: aflatoxin B1; Aspergillus; Aspergillus spp; Birds; farm; Farm buildings; Farms; Feeds; Fluconazole; Fungal infections; Fungi; Investigations; Laboratories; Livestock; Mycosis; Mycotoxins; Poultry; Public health; Respiratory diseases; Spores; Tropical diseases; Tuberculosis; Ventilation; Veterinary medicine; United States > US
• ISSN: 2309-608X; 2309-608X
• DOI: 10.3390/jof8111213

Among the fungi responsible for deep mycosis, the genus Aspergillus plays a predominant role both in human and veterinary medicine. From a “One Health” perspective, infections by Aspergillus spp. often represent a public health problem linked to specific occupational categories that could have a greater risk of inhaling spores and developing any respiratory disease. This preliminary investigation allowed to acquire information about the spread of Aspergillus spp. in avian livestock of the Umbria region (Central Italy), their sensitivity to antifungals, and the presence of mycotoxins in the considered farms. Environmental, feed, animal, and human samples were collected for mycological investigations; chemical analyses were also performed in feed samples. Moreover, prevalence estimated of the fungal isolates were provided for each individual farm sampled. Direct fungal identification was possible in 298 out of the 559 total samples; 162 of the samples were positive for Aspergillus spp. Mycotoxins were detected in 5 out of the 21 feed samples collected. All the aspergilli tested for antifungal susceptibility were resistant to fluconazole. The results obtained show how much the genus Aspergillus is widespread in the investigated farms; therefore, the poultry livestock represents a favorable environment for the maintenance and spread of fungal spores and their potential transmission to animals and humans.