Prenylation of Flavonoids by Using a Dimethylallyltryptophan Synthase, 7-DMATS, from Aspergillus fumigatus

• Published in: Chembiochem : a European journal of chemical biology Vol. 12; no. 15; pp. 2280 - 2283
• Main Authors: Yu, Xia, Li, Shu-Ming
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 17.10.2011; WILEY‐VCH Verlag
• Subjects: Alkyl and Aryl Transferases - metabolism; Aspergillus fumigatus - enzymology; Aspergillus fumigatus - metabolism; flavonoids; Flavonoids - chemistry; Flavonoids - metabolism; fungi; indoles; Prenylation; Recombinant Proteins - metabolism; synthases; transferases

Production of typical plant metabolites by a fungal enzyme: Fungal prenyltransferases of the DMATS superfamily are mainly involved in the biosynthesis of prenylated indole alkaloids, but also catalyze the prenylation of tyrosine and naphthalene derivatives. In this study, nine prenylated flavonoids...