Prenylation of Flavonoids by Using a Dimethylallyltryptophan Synthase, 7-DMATS, from Aspergillus fumigatus

Production of typical plant metabolites by a fungal enzyme: Fungal prenyltransferases of the DMATS superfamily are mainly involved in the biosynthesis of prenylated indole alkaloids, but also catalyze the prenylation of tyrosine and naphthalene derivatives. In this study, nine prenylated flavonoids...

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Published inChembiochem : a European journal of chemical biology Vol. 12; no. 15; pp. 2280 - 2283
Main Authors Yu, Xia, Li, Shu-Ming
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 17.10.2011
WILEY‐VCH Verlag
Subjects
Alkyl and Aryl Transferases - metabolism
Aspergillus fumigatus - enzymology
Aspergillus fumigatus - metabolism
flavonoids
Flavonoids - chemistry
Flavonoids - metabolism
fungi
indoles
Prenylation
Recombinant Proteins - metabolism
synthases
transferases
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Summary:Production of typical plant metabolites by a fungal enzyme: Fungal prenyltransferases of the DMATS superfamily are mainly involved in the biosynthesis of prenylated indole alkaloids, but also catalyze the prenylation of tyrosine and naphthalene derivatives. In this study, nine prenylated flavonoids were produced by using the recombinant dimethylallyltryptophan synthase 7‐DMATS from Aspergillus fumigatus.
Bibliography:ark:/67375/WNG-RJ7B2JV2-Q
China Scholarship Council
ArticleID:CBIC201100413
istex:C7C2E25F819885DCC10546F6410E744519EBED63
State of Hessen
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1439-4227
1439-7633
1439-7633
DOI:10.1002/cbic.201100413