Deproteinized bovine bone in periodontal and implant surgery

• Published in: Dental materials Vol. 27; no. 1; pp. 61 - 70
• Main Authors: Baldini, N, De Sanctis, M, Ferrari, M
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2011
• Subjects: Advanced Basic Science; Alveolar Ridge Augmentation; Animals; Anorganic bovine bone mineral; Bio-Oss; Bone Substitutes - therapeutic use; Bone Transplantation - methods; Cattle; Dental Implants; Dentistry; Deproteinized bovine bone; Guided Tissue Regeneration, Periodontal; Humans; Minerals - therapeutic use; Osteogenesis - physiology; Peri-implant reconstruction; Periodontal Diseases - surgery; Periodontal regeneration; Reconstructive Surgical Procedures; Socket preservation; Tissue Preservation - methods; Periodontal regeneration; Anorganic bovine bone mineral; Bio-Oss; Deproteinized bovine bone; Socket preservation; Peri-implant reconstruction
• ISSN: 0109-5641; 1879-0097
• DOI: 10.1016/j.dental.2010.10.017

Abstract Objectives To review the histological and clinical outcomes of deproteinized bovine bone in different procedures: periodontal regeneration, socket preservation, peri-implant reconstruction and alveolar bone augmentation. Methods Histological animal studies and clinical trials on humans regarding the performances of a bone substitute of natural origin, deproteinized bovine bone, have been evaluated. Different procedures have been examined separately. Results Osteoconductive properties of the material are accepted by the majority of authors. In periodontal regeneration deproteinized bovine bone seems to be effective with or without barrier membranes in favorable containing defects, resulting in histological evidence of periodontal regeneration, with a prevalence of bone repair. Although some reports describe a lower reduction in socket height and width with various techniques and the grafting of deproteinized bovine bone, there is no evidence to recommend socket filling or manipulation to preserve its dimensions. Peri-implant reconstruction and alveolar ridge augmentation utilizing deproteinized bovine bone are supported by favorable reports but these procedures are affected by a significant amount of adverse events that may jeopardize the success of the treatment. Significance Deproteinized bovine bone possesses osteoconductive properties that may improve bone regeneration of favorable containing periodontal defects. No evidence supports socket filling and peri-implant reconstruction.