Enhancement of Non-Invasive Recording of Electroenterogram by Means of a Flexible Array of Concentric Ring Electrodes

• Published in: Annals of biomedical engineering Vol. 42; no. 3; pp. 651 - 660
• Main Authors: Garcia-Casado, J., Zena-Gimenez, V., Prats-Boluda, G., Ye-Lin, Y.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.03.2014; Springer Nature B.V
• Subjects: Adult; Biochemistry; Biological and Medical Physics; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Biophysics; Classical Mechanics; Electrocardiography; Electrodes; Electromyography - instrumentation; Electromyography - methods; Female; Gastrointestinal Motility; Humans; Intestinal Diseases - diagnosis; Intestinal Diseases - pathology; Intestinal Diseases - physiopathology; Intestines - blood supply; Intestines - pathology; Intestines - physiopathology; Ischemia - diagnosis; Ischemia - pathology; Ischemia - physiopathology; Male; Intestinal slow wave; Gastrointestinal disorders; Laplacian recording; Screen-printing technology
• ISSN: 0090-6964; 1573-9686
• DOI: 10.1007/s10439-013-0935-y

Monitoring intestinal myoelectrical activity by electroenterogram (EEnG) would be of great clinical interest for diagnosing gastrointestinal pathologies and disorders. However, surface EEnG recordings are of very low amplitude and can be severely affected by baseline drifts and respiratory and electrocardiographic (ECG) interference. In this work, a flexible array of concentric ring electrodes was developed and tested to determine whether it can provide surface EEnG signals of better quality than bipolar recordings from conventional disc electrodes. With this aim, sixteen healthy subjects in a fasting state (>8 h) underwent recording. The capability of detecting intestinal pacemaker activity (slow wave) and the influence of physiological interferences were studied. The signals obtained from the concentric ring electrodes proved to be more robust to ECG and respiratory interference than those from conventional disc electrodes. The results also show that intestinal EEnG components such as the slow wave can be more easily identified by the proposed system based on a flexible array of concentric ring electrodes. The developed active electrode array could be a very valuable tool for non-invasive diagnosis of disease states such as ischemia and motility disorders of the small bowel which are known to alter the normal enteric slow wave activity.