Fluid and Electrolyte Disturbances in COVID-19 and Their Complications

• Published in: BioMed research international Vol. 2021; pp. 6667047 - 5
• Main Authors: Pourfridoni, Mohammad, Abbasnia, Seyede Mahsa, Shafaei, Fateme, Razaviyan, Javad, Heidari-Soureshjani, Reza
• Format: Journal Article
• Language: English
• Published: United States Hindawi 2021; Hindawi Limited
• Subjects: ACE2; Acute Kidney Injury - etiology; Angiotensin; Angiotensin-converting enzyme 2; Body Fluids - metabolism; Complications; Coronaviruses; COVID-19; COVID-19 - complications; COVID-19 - etiology; Disturbances; Electrolytes - metabolism; Gastrointestinal tract; Gastrointestinal Tract - physiopathology; Gastrointestinal Tract - virology; Humans; Hypernatremia; Hypervolemia; Hypocalcemia; Hypocalcemia - etiology; Hypokalemia; Hypokalemia - etiology; Hyponatremia; Hyponatremia - etiology; Hypovolemia; Kidney - physiopathology; Kidney - virology; Kidneys; Mortality; Peptidyl-dipeptidase A; Receptors; Review; Viral diseases; Viruses
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2021/6667047

The novel coronavirus disease 2019 (COVID-19) is the cause of an acute respiratory illness which has spread around the world. The virus infects the host by binding to the angiotensin-converting enzyme 2 (ACE2) receptors. Due to the presence of ACE2 receptors in the kidneys and gastrointestinal (GI) tract, kidneys and GI tract damage arising from the virus can be seen in patients and can cause acute conditions such as acute kidney injury (AKI) and digestive problems for the patient. One of the complications of kidneys and GI involvement in COVID-19 is fluid and electrolyte disturbances. The most common ones of these disorders are hyponatremia, hypernatremia, hypokalemia, hypocalcemia, hypochloremia, hypervolemia, and hypovolemia, which if left untreated, cause many problems for patients and even increase mortality. Fluid and electrolyte disturbances are more common in hospitalized and intensive care patients. Children are also at greater risk for fluid and electrolyte disturbances complications. Therefore, clinicians should pay special attention to the fluid and electrolyte status of patients. Changes in fluid and electrolyte levels can be a good indicator of disease progression.