Photodynamic therapy for choroidal neovascularisation secondary to basal laminar drusen

• Published in: Eye (London) Vol. 23; no. 11; pp. 2115 - 2118
• Main Authors: Guigui, B, Martinet, V, Leveziel, N, Coscas, G, Soubrane, G, Souied, E H
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.11.2009; Nature Publishing Group
• Subjects: Adult; Basement Membrane; Biological and medical sciences; case-series; Choroidal Neovascularization - drug therapy; Choroidal Neovascularization - etiology; Diseases of the skin. Cosmetics; Female; Humans; Laboratory Medicine; Male; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Miscellaneous; Ophthalmology; Pharmaceutical Sciences/Technology; Photochemotherapy - methods; Photosensitizing Agents - therapeutic use; Porphyrins - therapeutic use; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Retinal Drusen - complications; Surgery; Surgical Oncology; Treatment Outcome; Visual Acuity; choroidal neovascularisation; PDT; BLD; Secondary; Drusen; Photodynamic therapy; Treatment; Choroidal neovascularization; Ophthalmology
• ISSN: 0950-222X; 1476-5454
• DOI: 10.1038/eye.2009.239

Purpose Basal laminar drusen (BLD) is a rare retinal disorder that may be complicated with choroidal neovascularisation (CNV). Here we describe four patients treated with verteporfin photodynamic therapy (PDT) for CNV secondary to BLD. Methods Four consecutive patients presented with subfoveal CNV secondary to BLD. Mean visual acuity was 20/50. CNV was treated with one single PDT session. Results Exsudative features of CNV were resolved after one session for all patients. After 6 months, mean visual acuity was 20/25 and remained stable. Conclusion In this series, PDT was an effective treatment for CNV secondary to BLD.